Hyperbaric oxygen treatment restores sudden hearing loss in a patient with Fabry disease.
ORL J Otorhinolaryngol Relat Spec
; 70(3): 210-3, 2008.
Article
em En
| MEDLINE
| ID: mdl-18401198
ABSTRACT
Fabry disease is an X-linked inherited disorder of glycosphingolipid metabolism due to the deficient activity of a lysosomal enzyme, alpha-galactosidase A. The resultant systemic accumulation of sphingolipids can lead to progressive and sudden hearing loss alongside renal, cardiac and cerebrovascular complications. Although replacement therapy seems to be beneficial for cochlear function, few data are available regarding treatment of sudden hearing loss. This case report describes the course of a unilateral sudden hearing loss in a young (15-year-old) male patient and its improvement following hyperbaric oxygen treatment.
Texto completo:
1
Coleções:
01-internacional
Temas:
Geral
Base de dados:
MEDLINE
Assunto principal:
Doença de Fabry
/
Perda Auditiva Súbita
/
Perda Auditiva Unilateral
/
Oxigenoterapia Hiperbárica
Tipo de estudo:
Diagnostic_studies
Limite:
Adolescent
/
Humans
/
Male
Idioma:
En
Revista:
ORL J Otorhinolaryngol Relat Spec
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
Alemanha