[The lymphocyte acetylcholinesterase activity in rats poisoned by pesticides]. / Aktivnost' atsetilkholinésterazy limfotsitov krys pri intoksikatsii pestitsidami.
Biull Eksp Biol Med
; 111(2): 144-6, 1991 Feb.
Article
em Ru
| MEDLINE
| ID: mdl-1906760
ABSTRACT
The experiments carried out present the evidence of acetylcholinesterase activity of Wistar rat lymphocytes. It was shown that splenocytes and thymocytes had significantly different levels of the enzyme activity. Peroral administration of phosphor-organic pesticide antio (phormothion) 1/100 and 1/20 LD50 induced the dose-dependent inhibition of splenocyte acetylcholine-esterase activity after 2 months of treatment. It suggests the relation of the immunosuppressive action of pesticide with the interference into the neuromediator mechanisms regulating the lymphoid cell function.
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Coleções:
01-internacional
Temas:
Agentes_cancerigenos
Base de dados:
MEDLINE
Assunto principal:
Praguicidas
/
Acetilcolinesterase
/
Linfócitos
Limite:
Animals
Idioma:
Ru
Revista:
Biull Eksp Biol Med
Ano de publicação:
1991
Tipo de documento:
Article