The complete genome and genetic characteristics of SRV-4 isolated from cynomolgus monkeys (Macaca fascicularis).
Virology
; 405(2): 390-6, 2010 Sep 30.
Article
em En
| MEDLINE
| ID: mdl-20615522
ABSTRACT
At least 5 serotypes of exogenous simian retrovirus type D (SRV/D) have been found in nonhuman primates, but only SRV-1, 2 and 3 have been completely sequenced. SRV-4 was recovered once from cynomolgus macaques in California in 1984, but its genome sequences are unknown. Here we report the second identification of SRV-4 and its complete genome from infected cynomolgus macaques with Indochinese and Indonesian/Indochinese mixed ancestry. Phylogenetic analysis demonstrated that SRV-4 was distantly related to SRV-1, 2, 3, 5, 6 and 7. SRV/D-T, a new SRV/D recovered in 2005 from cynomolgus monkeys at Tsukuba Primate Center in Japan, clustered with the SRV-4 isolates from California and Texas and was shown to be another occurrence of SRV-4 infection. The repeated occurrence of SRV-4 in cynomolgus monkeys in different areas of the world and across 25years suggests that this species is the natural host of SRV-4.
Texto completo:
1
Coleções:
01-internacional
Temas:
Geral
Base de dados:
MEDLINE
Assunto principal:
Infecções Tumorais por Vírus
/
Genoma Viral
/
Análise de Sequência de DNA
/
Infecções por Retroviridae
/
Retrovirus dos Símios
/
Macaca fascicularis
/
Doenças dos Macacos
Tipo de estudo:
Prognostic_studies
Limite:
Animals
País/Região como assunto:
America do norte
/
Asia
Idioma:
En
Revista:
Virology
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
Estados Unidos