Dosimetric verification of the anisotropic analytical algorithm in lung equivalent heterogeneities with and without bone equivalent heterogeneities.
Med Phys
; 37(8): 4456-63, 2010 Aug.
Article
em En
| MEDLINE
| ID: mdl-20879604
ABSTRACT
PURPOSE:
In this study, the authors evaluated the accuracy of dose calculations performed by the convolution/superposition based anisotropic analytical algorithm (AAA) in lung equivalent heterogeneities with and without bone equivalent heterogeneities.METHODS:
Calculations of PDDs using the AAA and Monte Carlo simulations (MCNP4C) were compared to ionization chamber measurements with a heterogeneous phantom consisting of lung equivalent and bone equivalent materials. Both 6 and 10 MV photon beams of 4 x 4 and 10 x 10 cm(2) field sizes were used for the simulations. Furthermore, changes of energy spectrum with depth for the heterogeneous phantom using MCNP were calculated.RESULTS:
The ionization chamber measurements and MCNP calculations in a lung equivalent phantom were in good agreement, having an average deviation of only 0.64 +/- 0.45%. For both 6 and 10 MV beams, the average deviation was less than 2% for the 4 x 4 and 10 x 10 cm(2) fields in the water-lung equivalent phantom and the 4 x 4 cm(2) field in the water-lung-bone equivalent phantom. Maximum deviations for the 10 x 10 cm(2) field in the lung equivalent phantom before and after the bone slab were 5.0% and 4.1%, respectively. The Monte Carlo simulation demonstrated an increase of the low-energy photon component in these regions, more for the 10 X 10 cm(2) field compared to the 4 x 4 cm(2) field.CONCLUSIONS:
The low-energy photon by Monte Carlo simulation component increases sharply in larger fields when there is a significant presence of bone equivalent heterogeneities. This leads to great changes in the build-up and build-down at the interfaces of different density materials. The AAA calculation modeling of the effect is not deemed to be sufficiently accurate.
Texto completo:
1
Coleções:
01-internacional
Temas:
Geral
Base de dados:
MEDLINE
Assunto principal:
Radiometria
/
Osso e Ossos
/
Algoritmos
/
Planejamento da Radioterapia Assistida por Computador
/
Pulmão
/
Modelos Biológicos
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
En
Revista:
Med Phys
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
Japão