Update and review of central retinal vein occlusion.

PURPOSE OF REVIEW: To review the clinical picture of central retinal vein occlusion (CRVO), with an emphasis on recent therapeutic developments. RECENT FINDINGS: The most significant advances with regard to CRVO relate to the establishment of the important role of intravitreal anti-vascular endothelial growth factor and corticosteroids in the treatment of macular edema associated with vein occlusion. SUMMARY: Important objectives on evaluation of a patient presenting with a CRVO include differentiation between ischemic and nonischemic types, identification of any complications, and establishment of a treatment and/or follow-up plan. Macular edema is one of the main causes of vision loss in CRVO, and for the first time we can have effective treatment options for affected patients.