Oral squamous cell carcinoma: clinicopathological features in patients with and without recurrence.
ORL J Otorhinolaryngol Relat Spec
; 73(3): 170-6, 2011.
Article
em En
| MEDLINE
| ID: mdl-21625192
ABSTRACT
AIM:
To compare the clinicopathological profile of oral squamous cell carcinoma (OSCC) in groups with and without recurrence.METHODS:
Records of all patients who underwent surgery for primary OSCC at a single institution during 1999 were identified. Patient demographics, lesion site, clinical and pathologic stage, pathologic grading, pattern of invasion, lymphocytic infiltrate, perineural invasion, and treatment and survival data were collected. Descriptive statistics were calculated for each variable and survival was calculated using Kaplan-Meier and Cox models. Patients were divided into 2 groups with (n = 25) and without (n = 28) recurrence.RESULTS:
Tongue (p = 0.02) and poorly differentiated (p = 0.04) tumors were associated with recurrence. Kaplan-Meier and Cox models revealed tobacco use and the absence of lymphocytic infiltrate to be associated with the poorest survival in recurrent OSCC.CONCLUSION:
The tumor site, tobacco use, and pathological features were involved in the recurrence of OSCC and should be taken into account for OSCC treatment and follow-up.
Texto completo:
1
Coleções:
01-internacional
Temas:
Mortalidade
/
Geral
/
Tipos_de_cancer
/
Boca
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Bucais
/
Carcinoma de Células Escamosas
/
Recidiva Local de Neoplasia
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
ORL J Otorhinolaryngol Relat Spec
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Brasil