Chronic Hepatitis E as a cause for cryptogenic cirrhosis in HIV.
J Infect
; 66(1): 103-6, 2013 Jan.
Article
em En
| MEDLINE
| ID: mdl-22166370
ABSTRACT
Chronic Hepatitis E infection (HEV) is reported in immunocompromised patients. A 45-year-old HIV-infected man had no cause found for a persistent transaminitis which predated commencement of antiretroviral therapy. Hepatic elastography and liver biopsy revealed cirrhosis. In 2010, he tested positive for HEV IgM/IgG antibodies. Plasma HEV RNA was detected. Archived samples revealed HEV viraemia since 2000. A 24-week course of pegylated interferon was commenced and HEV RNA became undetectable at week 4 until week 27 post treatment cessation. Chronic HEV infection should be considered in HIV patients as a cause for unexplained transaminitis and cryptogenic liver cirrhosis.
Texto completo:
1
Coleções:
01-internacional
Temas:
Geral
Base de dados:
MEDLINE
Assunto principal:
Infecções por HIV
/
Hepatite E
/
Hepatite Crônica
/
Cirrose Hepática
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
J Infect
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Reino Unido