Modified Roux-en-Y gastric bypass for type 2 diabetes mellitus in China.
Hepatogastroenterology
; 60(121): 129-31, 2013.
Article
em En
| MEDLINE
| ID: mdl-22829557
ABSTRACT
BACKGROUND/AIMS:
This study aimed to evaluate the efficacy of modified Roux-en-Y gastric bypass for type 2 diabetes mellitus.METHODOLOGY:
Forty-five type 2 diabetes mellitus patients underwent modified Roux-en-Y gastric bypass at WeiFang People's Hospital. Data on patient demographics, fasting plasma glucose (FPG), body mass index (BMI), medication use, remission and hemoglobin A1c (HbAlc) were prospectively collected and analyzed.RESULTS:
At 6 months after surgery, all of these 45 patients obtained remission or a marked improvement. FPG was in the normal range in 39 (86.7%) patients stopping medicine treatment for their diabetes. Six patients (13.3%) had an obvious reduced abnormal FPG and they only required lower drug dosage. No statistically significant differences were found between the obese or non-obese groups (p=0.311). The mean BMI dropped from 28.9±3.0 kg/m2 to 27.4±2.8 kg/m2 (p=0.000) at the third month and 26.3±2.5 kg/m2 (p=0.000) at the sixth month. HbAlc decreased from their preoperative values of 7.4%±2.2% to 6.3%±1.5% (p=0.000) at the third month and 5.1%±0.9% (p=0.000) at the sixth month.CONCLUSIONS:
Modified Roux-en-Y gastric bypass was effective in treating type 2 diabetes mellitus, independent of body mass index.
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Coleções:
01-internacional
Temas:
Geral
Base de dados:
MEDLINE
Assunto principal:
Derivação Gástrica
/
Diabetes Mellitus Tipo 2
Tipo de estudo:
Observational_studies
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
País/Região como assunto:
Asia
Idioma:
En
Revista:
Hepatogastroenterology
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
China