Static renal scintigraphy with 99mTc-DMSA for the assessment of renal damage after therapy for acute lymphoblastic leukemia in children.
Ann Acad Med Stetin
; 57(2): 5-9, 2011.
Article
em En
| MEDLINE
| ID: mdl-23002662
ABSTRACT
INTRODUCTION:
Acute lymphoblastic leukemia (ALL) and its treatment may adversely affect kidney function. The aim of the present study was to determine whether 99mTc-DMSA static renal scintigraphy can be used to disclose kidney damage at the end of therapy for ALL in children. MATERIAL ANDMETHODS:
The study group consisted of 48 ALL patients aged 6.6-22.9 years, with a mean time of continuous complete remission of 51 months. Static renal scintigraphy with 99mTc-DMSA was performed in all patients.RESULTS:
Minor scars in the renal cortex were diagnosed with scintigraphy in 6 (13%) patients. A significant correlation was found between renal scarring and a history of urinary tract infection.CONCLUSIONS:
No clinically significant kidney damage was found after completion of treatment of ALL. Static renal scintigraphy may be a valuable noninvasive method for visualization of renal cortex pathology.
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Coleções:
01-internacional
Temas:
Geral
/
Tipos_de_cancer
/
Leucemia
Base de dados:
MEDLINE
Assunto principal:
Infecções Urinárias
/
Cicatriz
/
Leucemia-Linfoma Linfoblástico de Células Precursoras
/
Nefropatias
Tipo de estudo:
Etiology_studies
Limite:
Adolescent
/
Adult
/
Child
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Ann Acad Med Stetin
Ano de publicação:
2011
Tipo de documento:
Article