Purification of cytochrome P-450 enzymes.
Curr Protoc Toxicol
; Chapter 4: Unit4.2, 2002.
Article
em En
| MEDLINE
| ID: mdl-23045082
ABSTRACT
Among the liver P-450 xenobiotic-metabolizing enzymes, P450-2E1 is of interest because of its activation of potent carcinogens, and P-450 1A2 is of interest because of its role in oxidation of drugs and carcinogens. This unit describes column chromatography protocols for purification of recombinant forms of these enzymes expressed in a bacterial expression system.
Texto completo:
1
Coleções:
01-internacional
Temas:
Geral
Base de dados:
MEDLINE
Assunto principal:
Sistema Enzimático do Citocromo P-450
/
Isoenzimas
Limite:
Humans
Idioma:
En
Revista:
Curr Protoc Toxicol
Ano de publicação:
2002
Tipo de documento:
Article
País de afiliação:
Estados Unidos