Familial synchronous bilateral teratoid Wilms tumor with elevated alpha-fetoprotein level.
Tumori
; 98(6): 179e-82e, 2012 Nov.
Article
em En
| MEDLINE
| ID: mdl-23389381
ABSTRACT
Familial Wilms tumor is a rare entity that accounts for only 1-2% of all Wilms tumor cases, with an earlier age of onset and an increased frequency of bilateral tumors. Teratoid Wilms tumor is a variant of nephroblastoma with a predominance of heterologous tissues comprising more than 50% of the tumor volume. Wilms tumor does not usually secrete any specific tumor marker and all teratoid Wilms tumor cases previously reported were sporadic non-secreting neoplasms. Here we describe an infant with familial synchronous bilateral teratoid Wilms tumor whose serum alpha-fetoprotein level was elevated. To our knowledge, this extremely rare type of case is reported for the first time in the literature.
Texto completo:
1
Coleções:
01-internacional
Temas:
Geral
/
Prevencao_e_fatores_de_risco
/
Hereditariedade
/
Tipos_de_cancer
/
Outros_tipos
Base de dados:
MEDLINE
Assunto principal:
Alfa-Fetoproteínas
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Biomarcadores Tumorais
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Tumor de Wilms
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Metilenotetra-Hidrofolato Redutase (NADPH2)
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Neoplasias Renais
/
Neoplasias Primárias Múltiplas
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
Limite:
Humans
/
Infant
/
Male
Idioma:
En
Revista:
Tumori
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Turquia