Erythrocyte omega-6 and omega-3 fatty acids and mammographic breast density.
Nutr Cancer
; 65(3): 410-6, 2013.
Article
em En
| MEDLINE
| ID: mdl-23530640
ABSTRACT
Diets low in omega-6 (n-6) polyunsaturated fatty acids (PUFAs) and high in omega-3 (n-3) PUFAs may protect against breast cancer development. Associations of PUFA intake with mammographic density, an intermediate marker of breast cancer risk, have been inconsistent; however, prior studies have relied on self-reported dietary PUFA intake. We examined the association between circulating erythrocyte n-6 and n-3 PUFAs with mammographic density in 248 postmenopausal women who were not taking exogenous hormones. PUFAs in erythrocytes were measured by gas-liquid chromatography, and mammographic density was assessed quantitatively by planimetry. Spearman's correlation coefficients and generalized linear models were used to evaluate the relationships between PUFA measures and mammographic density. None of the erythrocyte n-6 or n-3 PUFA measures were associated with percent density or dense breast area.
Texto completo:
1
Coleções:
01-internacional
Temas:
Geral
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Tipos_de_cancer
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Outros_tipos
Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Mama
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Ácidos Graxos Ômega-3
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Ácidos Graxos Ômega-6
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Eritrócitos
Limite:
Aged
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Female
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Humans
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Middle aged
Idioma:
En
Revista:
Nutr Cancer
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Estados Unidos