Esophageal atresia, small omphalocele and ileal prolapse through a patent omphalomesenteric duct: a methimazole embryopathy? [Corrected].
J Pediatr Surg
; 48(6): E9-11, 2013 Jun.
Article
em En
| MEDLINE
| ID: mdl-23845657
ABSTRACT
Newborns prenatally exposed to methimazole (active metabolite of carbamizole) for maternal hyperthyroidism may present some disorders in common, but the phenotype is not well defined. Choanal atresia is the most frequent, and other anomalies such as esophageal atresia and aplasia cutis were described with this embryopathy. Additionally, patent omphalomesenteric duct or Meckel's diverticulum in similar association was reported in some patients. The predisposed genetic background has to be considered. We report the case of a newborn exposed to carbamizole during the first 4 weeks of pregnancy and define an association related to prenatal methamizole exposure consisting of esophageal atresia, small omphalocele, and ileal prolapse through a patent omphalomesenteric duct.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Temas:
Geral
Base de dados:
MEDLINE
Assunto principal:
Anormalidades Múltiplas
/
Anti-Inflamatórios não Esteroides
/
Dipirona
/
Lesões Pré-Natais
/
Atresia Esofágica
/
Hérnia Umbilical
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Divertículo Ileal
Tipo de estudo:
Diagnostic_studies
Limite:
Female
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Humans
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Newborn
/
Pregnancy
Idioma:
En
Revista:
J Pediatr Surg
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
França