Proteína da Polipose Adenomatosa do Colo/genética; Biomarcadores Tumorais/genética; Neoplasias Colorretais/genética; Regulação Neoplásica da Expressão Gênica; Animais; Biomarcadores Tumorais/sangue; Neoplasias Colorretais/sangue; Neoplasias Colorretais/patologia; Deleção de Genes; Humanos; Mucosa Intestinal/metabolismo; Mucosa Intestinal/fisiologia; Camundongos; Camundongos Transgênicos; Proibitinas; Proteômica

Adenomatous polyposis coli; AhCre(+)Apc(+/+); AhCre(+)Apc(fl)(/)(fl); Apc; Apc(Min/+); Biomarkers; CK18; CRC; CTBRC; Cancer Tissue Bank Research Centre; Colorectal cancer; Cytokeratin 18; DDX5; DEAD (Asp-Glu-Ala-Asp) box polypeptide 5; ECE; FAP; FDR; HSPD1; IHC; IPA; LC MS/MS; MMTS; NCL; Nucleolin; PCR; PHB; Prohibitin; Proteomics; ROC; RPL6; Ribosomal protein L6; SEM; TCEP; TEAB; TFA; WB; acute conditional transgenic deletion of the Apc gene in the murine intestinal epithelium; adenomatous polyposis coli; epithelial cell extracts; false discovery rate; familial adenomatous polyposis; gFOBt; germline mutations in the Apc gene, spontaneously develop multiple intestinal adenomas; guaiac faecal blood test; heat shock 60kDa protein 1 (chaperonin); i.p.; iTRAQ; immunohistochemistry; ingenuity pathways analysis; intra-peritoneal; isobaric tags for relative and absolute quantification; liquid chromatography­mass spectrometry; methylmethanethiosulfonate; polymerase chain reaction; receiver operating characteristic; standard error of mean; triethylammonium bicarbonate; trifluoroacetic acid; tris(2-carboxyethyl)phosphine; western blotting; wild type control for acute conditional transgenic deletion of the Apc gene in the murine intestinal epithelium