PTEN inhibits the invasion and metastasis of gastric cancer via downregulation of FAK expression.

Zhang, Ling-Li; Liu, Jie; Lei, Shen; Zhang, Jun; Zhou, Wei; Yu, Hong-Gang

Zhang, Ling-Li; Liu, Jie; Lei, Shen; Zhang, Jun; Zhou, Wei; Yu, Hong-Gang.

Afiliação

Zhang LL; Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, People's Republic of China; Institute for Gastroenterology and Hepatology, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, People's Republic of China.
Liu J; Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, People's Republic of China; Institute for Gastroenterology and Hepatology, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, People's Republic of China.
Lei S; Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, People's Republic of China; Institute for Gastroenterology and Hepatology, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, People's Republic of China.
Zhang J; Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, People's Republic of China; Institute for Gastroenterology and Hepatology, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, People's Republic of China.
Zhou W; Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, People's Republic of China; Institute for Gastroenterology and Hepatology, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, People's Republic of China.
Yu HG; Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, People's Republic of China; Institute for Gastroenterology and Hepatology, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, People's Republic of China. Electronic address: yhgwhu@gmai

Cell Signal ; 26(5): 1011-20, 2014 May.

Article em En | MEDLINE | ID: mdl-24486402

Assuntos

Regulação para Baixo; Proteína-Tirosina Quinases de Adesão Focal/genética; PTEN Fosfo-Hidrolase/metabolismo; Neoplasias Gástricas/fisiopatologia; Substituição de Aminoácidos; Animais; Linhagem Celular Tumoral; Feminino; Proteína-Tirosina Quinases de Adesão Focal/metabolismo; Regulação Neoplásica da Expressão Gênica; Humanos; Neoplasias Hepáticas/patologia; Neoplasias Hepáticas/secundário; Camundongos; Camundongos Nus; NF-kappa B/metabolismo; PTEN Fosfo-Hidrolase/antagonistas & inibidores; PTEN Fosfo-Hidrolase/genética; Neoplasias Peritoneais/patologia; Neoplasias Peritoneais/secundário; Fosfatidilinositol 3-Quinase/metabolismo; Regiões Promotoras Genéticas; Ligação Proteica; Transdução de Sinais; Neoplasias Gástricas/metabolismo; Transplante Heterólogo

Palavras-chave

Focal adhesion kinase; Migration; Transcription; Tumorigenicity

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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Estomago Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / Regulação para Baixo / PTEN Fosfo-Hidrolase / Proteína-Tirosina Quinases de Adesão Focal Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Cell Signal Ano de publicação: 2014 Tipo de documento: Article

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