Pseudomonas-derived ceramidase induces production of inflammatory mediators from human keratinocytes via sphingosine-1-phosphate.

Oizumi, Ami; Nakayama, Hitoshi; Okino, Nozomu; Iwahara, Chihiro; Kina, Katsunari; Matsumoto, Ryo; Ogawa, Hideoki; Takamori, Kenji; Ito, Makoto; Suga, Yasushi; Iwabuchi, Kazuhisa

Oizumi, Ami; Nakayama, Hitoshi; Okino, Nozomu; Iwahara, Chihiro; Kina, Katsunari; Matsumoto, Ryo; Ogawa, Hideoki; Takamori, Kenji; Ito, Makoto; Suga, Yasushi; Iwabuchi, Kazuhisa.

Afiliação

Oizumi A; Institute for Environmental and Gender-specific Medicine, Juntendo University Graduate School of Medicine, Urayasu, Japan ; Department of Dermatology, Juntendo University Urayasu Hospital, Urayasu, Japan.
Nakayama H; Institute for Environmental and Gender-specific Medicine, Juntendo University Graduate School of Medicine, Urayasu, Japan ; Laboratory of Biochemistry, Juntendo University School of Health Care and Nursing, Urayasu, Japan.
Okino N; Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Fukuoka, Japan.
Iwahara C; Institute for Environmental and Gender-specific Medicine, Juntendo University Graduate School of Medicine, Urayasu, Japan.
Kina K; Institute for Environmental and Gender-specific Medicine, Juntendo University Graduate School of Medicine, Urayasu, Japan.
Matsumoto R; Institute for Environmental and Gender-specific Medicine, Juntendo University Graduate School of Medicine, Urayasu, Japan.
Ogawa H; Institute for Environmental and Gender-specific Medicine, Juntendo University Graduate School of Medicine, Urayasu, Japan.
Takamori K; Institute for Environmental and Gender-specific Medicine, Juntendo University Graduate School of Medicine, Urayasu, Japan ; Department of Dermatology, Juntendo University Urayasu Hospital, Urayasu, Japan.
Ito M; Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Fukuoka, Japan.
Suga Y; Department of Dermatology, Juntendo University Urayasu Hospital, Urayasu, Japan.
Iwabuchi K; Institute for Environmental and Gender-specific Medicine, Juntendo University Graduate School of Medicine, Urayasu, Japan ; Laboratory of Biochemistry, Juntendo University School of Health Care and Nursing, Urayasu, Japan.

PLoS One ; 9(2): e89402, 2014.

Article em En | MEDLINE | ID: mdl-24586752

Assuntos

Mediadores da Inflamação/metabolismo; Queratinócitos/metabolismo; Lisofosfolipídeos/metabolismo; Ceramidase Neutra/metabolismo; Pseudomonas/metabolismo; Esfingosina/análogos & derivados; Células Cultivadas; Endotelina-1/metabolismo; Humanos; Proteínas I-kappa B/metabolismo; Interleucina-8/metabolismo; Inibidor de NF-kappaB alfa; Fosfotransferases (Aceptor do Grupo Álcool)/metabolismo; Receptores de Lisoesfingolipídeo/metabolismo; Esfingosina/metabolismo; Fator de Transcrição RelA/metabolismo; Fator de Necrose Tumoral alfa/metabolismo

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Pseudomonas / Esfingosina / Lisofosfolipídeos / Queratinócitos / Mediadores da Inflamação / Ceramidase Neutra Limite: Humans Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Japão

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