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Combination treatment of r-tPA and an optimized human apyrase reduces mortality rate and hemorrhagic transformation 6h after ischemic stroke in aged female rats.
Tan, Zhenjun; Li, Xinlan; Turner, Ryan C; Logsdon, Aric F; Lucke-Wold, Brandon; DiPasquale, Kenneth; Jeong, Soon Soeg; Chen, Ridong; Huber, Jason D; Rosen, Charles L.
Afiliação
  • Tan Z; Department of Neurosurgery, West Virginia University School of Medicine, Health Sciences Center, One Medical Center Drive, Suite 4300, PO Box 9183, Morgantown, WV 26506-9183, USA.
  • Li X; Department of Neurosurgery, West Virginia University School of Medicine, Health Sciences Center, One Medical Center Drive, Suite 4300, PO Box 9183, Morgantown, WV 26506-9183, USA.
  • Turner RC; Department of Neurosurgery, West Virginia University School of Medicine, Health Sciences Center, One Medical Center Drive, Suite 4300, PO Box 9183, Morgantown, WV 26506-9183, USA.
  • Logsdon AF; Department of Basic Pharmaceutical Sciences, West Virginia University, Morgantown, WV 26505, USA.
  • Lucke-Wold B; Department of Neurosurgery, West Virginia University School of Medicine, Health Sciences Center, One Medical Center Drive, Suite 4300, PO Box 9183, Morgantown, WV 26506-9183, USA.
  • DiPasquale K; Department of Basic Pharmaceutical Sciences, West Virginia University, Morgantown, WV 26505, USA.
  • Jeong SS; APT Therapeutics Inc, St. Louis, MO 63108, USA.
  • Chen R; APT Therapeutics Inc, St. Louis, MO 63108, USA.
  • Huber JD; Department of Basic Pharmaceutical Sciences, West Virginia University, Morgantown, WV 26505, USA.
  • Rosen CL; Department of Neurosurgery, West Virginia University School of Medicine, Health Sciences Center, One Medical Center Drive, Suite 4300, PO Box 9183, Morgantown, WV 26506-9183, USA. Electronic address: crosen@hsc.wvu.edu.
Eur J Pharmacol ; 738: 368-73, 2014 Sep 05.
Article em En | MEDLINE | ID: mdl-24933645
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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Apirase / Proteínas Recombinantes / Hemorragia Cerebral / Ativador de Plasminogênio Tecidual / Infarto da Artéria Cerebral Média Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Eur J Pharmacol Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Apirase / Proteínas Recombinantes / Hemorragia Cerebral / Ativador de Plasminogênio Tecidual / Infarto da Artéria Cerebral Média Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Eur J Pharmacol Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos