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Synthesis, anticancer activity and toxicity of a water-soluble 4S,5S-derivative of heptaplatin, cis-{Pt(II)[(4S,5S)-4,5-bis(aminomethyl)-2-isopropyl-1,3-dioxolane]·(3-hydroxyl-cyclobutane-1,1-dicarboxylate)}.
Liu, Weiping; Jiang, Jing; Xie, Chengying; Hou, Shuqian; Quan, Haitian; Ye, Qingsong; Lou, Liguang.
Afiliação
  • Liu W; State Key Laboratory for Platinum Group Metals, Kunming Institute of Precious Metals, 650106 Yunnan, PR China.
  • Jiang J; State Key Laboratory for Platinum Group Metals, Kunming Institute of Precious Metals, 650106 Yunnan, PR China.
  • Xie C; Shanghai Institute of Materia Medica, Chinese Academy of Science, Shanghai 201203, PR China.
  • Hou S; State Key Laboratory for Platinum Group Metals, Kunming Institute of Precious Metals, 650106 Yunnan, PR China.
  • Quan H; Shanghai Institute of Materia Medica, Chinese Academy of Science, Shanghai 201203, PR China.
  • Ye Q; State Key Laboratory for Platinum Group Metals, Kunming Institute of Precious Metals, 650106 Yunnan, PR China.
  • Lou L; Shanghai Institute of Materia Medica, Chinese Academy of Science, Shanghai 201203, PR China. Electronic address: liguanglou1@126.com.
J Inorg Biochem ; 140: 126-30, 2014 Nov.
Article em En | MEDLINE | ID: mdl-25108185
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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Compostos Organoplatínicos / Malonatos / Antineoplásicos Limite: Humans Idioma: En Revista: J Inorg Biochem Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Compostos Organoplatínicos / Malonatos / Antineoplásicos Limite: Humans Idioma: En Revista: J Inorg Biochem Ano de publicação: 2014 Tipo de documento: Article