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Primary Epstein-Barr virus infection and probable parvovirus B19 reactivation resulting in fulminant hepatitis and fulfilling five of eight criteria for hemophagocytic lymphohistiocytosis.
Karrasch, Matthias; Felber, Jörg; Keller, Peter M; Kletta, Christine; Egerer, Renate; Bohnert, Jürgen; Hermann, Beate; Pfister, Wolfgang; Theis, Bernhard; Petersen, Iver; Stallmach, Andreas; Baier, Michael.
Afiliação
  • Karrasch M; Institute of Medical Microbiology, University Hospital, Friedrich-Schiller-University, Erlanger Allee 101, 07743 Jena, Germany. Electronic address: matthias.karrasch@med.uni-jena.de.
  • Felber J; Department of Internal Medicine IV, University Hospital, Friedrich-Schiller-University, Jena, Germany.
  • Keller PM; Department of Internal Medicine IV, University Hospital, Friedrich-Schiller-University, Jena, Germany.
  • Kletta C; Emergency Room, University Hospital, Friedrich-Schiller-University, Jena, Germany.
  • Egerer R; Institute of Medical Microbiology, University Hospital, Friedrich-Schiller-University, Erlanger Allee 101, 07743 Jena, Germany.
  • Bohnert J; Institute of Medical Microbiology, University Hospital, Friedrich-Schiller-University, Erlanger Allee 101, 07743 Jena, Germany.
  • Hermann B; Institute of Medical Microbiology, University Hospital, Friedrich-Schiller-University, Erlanger Allee 101, 07743 Jena, Germany.
  • Pfister W; Institute of Medical Microbiology, University Hospital, Friedrich-Schiller-University, Erlanger Allee 101, 07743 Jena, Germany.
  • Theis B; Institute of Pathology, University Hospital, Friedrich-Schiller-University, Jena, Germany.
  • Petersen I; Institute of Pathology, University Hospital, Friedrich-Schiller-University, Jena, Germany.
  • Stallmach A; Department of Internal Medicine IV, University Hospital, Friedrich-Schiller-University, Jena, Germany.
  • Baier M; Institute of Medical Microbiology, University Hospital, Friedrich-Schiller-University, Erlanger Allee 101, 07743 Jena, Germany.
Int J Infect Dis ; 28: 143-6, 2014 Nov.
Article em En | MEDLINE | ID: mdl-25242697
A case of primary Epstein-Barr virus (EBV) infection/parvovirus B19 reactivation fulfilling five of eight criteria for hemophagocytic lymphohistiocytosis (HLH) is presented. Despite two coinciding viral infections, massive splenomegaly, and fulminant hepatitis, the patient had a good clinical outcome, probably due to an early onset form of HLH with normal leukocyte count, normal natural killer (NK) cell function, and a lack of hemophagocytosis.
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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Parvovirus B19 Humano / Infecções por Parvoviridae / Infecções por Vírus Epstein-Barr / Linfo-Histiocitose Hemofagocítica / Coinfecção / Hepatite Limite: Adult / Humans / Male Idioma: En Revista: Int J Infect Dis Assunto da revista: DOENCAS TRANSMISSIVEIS Ano de publicação: 2014 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Parvovirus B19 Humano / Infecções por Parvoviridae / Infecções por Vírus Epstein-Barr / Linfo-Histiocitose Hemofagocítica / Coinfecção / Hepatite Limite: Adult / Humans / Male Idioma: En Revista: Int J Infect Dis Assunto da revista: DOENCAS TRANSMISSIVEIS Ano de publicação: 2014 Tipo de documento: Article