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Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer.
Ju, Young Seok; Alexandrov, Ludmil B; Gerstung, Moritz; Martincorena, Inigo; Nik-Zainal, Serena; Ramakrishna, Manasa; Davies, Helen R; Papaemmanuil, Elli; Gundem, Gunes; Shlien, Adam; Bolli, Niccolo; Behjati, Sam; Tarpey, Patrick S; Nangalia, Jyoti; Massie, Charles E; Butler, Adam P; Teague, Jon W; Vassiliou, George S; Green, Anthony R; Du, Ming-Qing; Unnikrishnan, Ashwin; Pimanda, John E; Teh, Bin Tean; Munshi, Nikhil; Greaves, Mel; Vyas, Paresh; El-Naggar, Adel K; Santarius, Tom; Collins, V Peter; Grundy, Richard; Taylor, Jack A; Hayes, D Neil; Malkin, David; Foster, Christopher S; Warren, Anne Y; Whitaker, Hayley C; Brewer, Daniel; Eeles, Rosalind; Cooper, Colin; Neal, David; Visakorpi, Tapio; Isaacs, William B; Bova, G Steven; Flanagan, Adrienne M; Futreal, P Andrew; Lynch, Andy G; Chinnery, Patrick F; McDermott, Ultan; Stratton, Michael R; Campbell, Peter J.
Afiliação
  • Ju YS; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, United Kingdom.
  • Alexandrov LB; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, United Kingdom.
  • Gerstung M; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, United Kingdom.
  • Martincorena I; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, United Kingdom.
  • Nik-Zainal S; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, United Kingdom.
  • Ramakrishna M; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, United Kingdom.
  • Davies HR; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, United Kingdom.
  • Papaemmanuil E; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, United Kingdom.
  • Gundem G; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, United Kingdom.
  • Shlien A; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, United Kingdom.
  • Bolli N; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, United Kingdom.
  • Behjati S; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, United Kingdom.
  • Tarpey PS; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, United Kingdom.
  • Nangalia J; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, United Kingdom.
  • Massie CE; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, United Kingdom.
  • Butler AP; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, United Kingdom.
  • Teague JW; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, United Kingdom.
  • Vassiliou GS; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, United Kingdom.
  • Green AR; Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
  • Du MQ; Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
  • Unnikrishnan A; Lowy Cancer Research Centre, University of New South Wales, Sydney, Australia.
  • Pimanda JE; Lowy Cancer Research Centre, University of New South Wales, Sydney, Australia.
  • Teh BT; Laboratory of Cancer Epigenome, National Cancer Centre, Singapore, Singapore.
  • Munshi N; Department of Hematologic Oncology, Dana-Farber Cancer Institute, Boston, United States.
  • Greaves M; Institute of Cancer Research, Sutton, London, United Kingdom.
  • Vyas P; Weatherall Institute for Molecular Medicine, University of Oxford, Oxford, United Kingdom.
  • El-Naggar AK; Department of Pathology, MD Anderson Cancer Center, Houston, United States.
  • Santarius T; Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
  • Collins VP; Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
  • Grundy R; Children's Brain Tumour Research Centre, University of Nottingham, Nottingham, United Kingdom.
  • Taylor JA; National Institute of Environmental Health Sciences, National Institute of Health, Triangle, North Carolina, United States.
  • Hayes DN; Department of Internal Medicine, University of North Carolina, Chapel Hill, United States.
  • Malkin D; Hospital for Sick Children, University of Toronto, Toronto, Canada.
  • Foster CS; Department of Molecular and Clinical Cancer Medicine, University of Liverpool, London, United Kingdom.
  • Warren AY; Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
  • Whitaker HC; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom.
  • Brewer D; Institute of Cancer Research, Sutton, London, United Kingdom.
  • Eeles R; Institute of Cancer Research, Sutton, London, United Kingdom.
  • Cooper C; Institute of Cancer Research, Sutton, London, United Kingdom.
  • Neal D; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom.
  • Visakorpi T; Institute of Biosciences and Medical Technology - BioMediTech and Fimlab Laboratories, University of Tampere and Tampere University Hospital, Tampere, Finland.
  • Isaacs WB; Department of Oncology, Johns Hopkins University, Baltimore, United States.
  • Bova GS; Institute of Biosciences and Medical Technology - BioMediTech and Fimlab Laboratories, University of Tampere and Tampere University Hospital, Tampere, Finland.
  • Flanagan AM; Department of Histopathology, Royal National Orthopaedic Hospital, Middlesex, United Kingdom.
  • Futreal PA; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, United Kingdom.
  • Lynch AG; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom.
  • Chinnery PF; Wellcome Trust Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastle-upon-tyne, United Kingdom.
  • McDermott U; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, United Kingdom.
  • Stratton MR; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, United Kingdom.
  • Campbell PJ; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, United Kingdom.
Elife ; 32014 Oct 01.
Article em En | MEDLINE | ID: mdl-25271376
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: DNA / DNA Mitocondrial / DNA de Neoplasias / Genoma Mitocondrial / Mutação / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Elife Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
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XML
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: DNA / DNA Mitocondrial / DNA de Neoplasias / Genoma Mitocondrial / Mutação / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Elife Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Reino Unido