UGT1A and UGT2B genetic variation alters nicotine and nitrosamine glucuronidation in european and african american smokers.

Wassenaar, Catherine A; Conti, David V; Das, Soma; Chen, Peixian; Cook, Edwin H; Ratain, Mark J; Benowitz, Neal L; Tyndale, Rachel F

Wassenaar, Catherine A; Conti, David V; Das, Soma; Chen, Peixian; Cook, Edwin H; Ratain, Mark J; Benowitz, Neal L; Tyndale, Rachel F.

Afiliação

Wassenaar CA; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada.
Conti DV; Department of Preventive Medicine, University of Southern California, Los Angeles, California.
Das S; Department of Human Genetics, University of Chicago, Chicago, Illinois.
Chen P; Department of Human Genetics, University of Chicago, Chicago, Illinois.
Cook EH; Department of Psychiatry, University of Illinois at Chicago, Chicago, Illinois.
Ratain MJ; Department of Medicine, Committee on Clinical Pharmacology and Pharmacogenomics, Cancer Research Center, University of Chicago, Chicago, Illinois.
Benowitz NL; Division of Clinical Pharmacology and Experimental Therapeutics, Department of Medicine, University of California San Francisco, San Francisco, California. Department of Bioengineering and Therapeutic Science, University of California San Francisco, San Francisco, California.
Tyndale RF; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada. Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, Canada. Department of Psychiatry, University of Toronto, Toronto, Ontario, Ca

Cancer Epidemiol Biomarkers Prev ; 24(1): 94-104, 2015 Jan.

Article em En | MEDLINE | ID: mdl-25277794

Assuntos

Negro ou Afro-Americano/genética; Glucuronosiltransferase/genética; Nicotina/metabolismo; Nitrosaminas/metabolismo; Fumar/genética; População Branca/genética; Adulto; Idoso; Variação Genética; Técnicas de Genotipagem; Humanos; Pessoa de Meia-Idade

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Negro ou Afro-Americano / Fumar / Glucuronosiltransferase / População Branca / Nicotina / Nitrosaminas Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Humans / Middle aged Idioma: En Revista: Cancer Epidemiol Biomarkers Prev Assunto da revista: BIOQUIMICA / EPIDEMIOLOGIA / NEOPLASIAS Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Canadá

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