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The BMP pathway either enhances or inhibits the Wnt pathway depending on the SMAD4 and p53 status in CRC.
Voorneveld, P W; Kodach, L L; Jacobs, R J; van Noesel, C J M; Peppelenbosch, M P; Korkmaz, K S; Molendijk, I; Dekker, E; Morreau, H; van Pelt, G W; Tollenaar, R A E M; Mesker, W; Hawinkels, L J A C; Paauwe, M; Verspaget, H W; Geraets, D T; Hommes, D W; Offerhaus, G J A; van den Brink, G R; Ten Dijke, P; Hardwick, J C H.
Afiliação
  • Voorneveld PW; Department of Gastroenterology and Hepatology, Leiden University Medical Center, Albinusdreef 2, 2300RC Leiden, The Netherlands.
  • Kodach LL; Department of Gastroenterology and Hepatology, Leiden University Medical Center, Albinusdreef 2, 2300RC Leiden, The Netherlands.
  • Jacobs RJ; Department of Gastroenterology and Hepatology, Leiden University Medical Center, Albinusdreef 2, 2300RC Leiden, The Netherlands.
  • van Noesel CJ; Department of Pathology, Academic Medical Center, Amsterdam, The Netherlands.
  • Peppelenbosch MP; Department of Gastroenterology and Hepatology, Erasmus MC, Erasmus University Rotterdam, Rotterdam, The Netherlands.
  • Korkmaz KS; Department of Gastroenterology and Hepatology, Leiden University Medical Center, Albinusdreef 2, 2300RC Leiden, The Netherlands.
  • Molendijk I; Department of Gastroenterology and Hepatology, Leiden University Medical Center, Albinusdreef 2, 2300RC Leiden, The Netherlands.
  • Dekker E; Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands.
  • Morreau H; Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.
  • van Pelt GW; Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands.
  • Tollenaar RA; Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands.
  • Mesker W; Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands.
  • Hawinkels LJ; 1] Department of Gastroenterology and Hepatology, Leiden University Medical Center, Albinusdreef 2, 2300RC Leiden, The Netherlands [2] Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands.
  • Paauwe M; Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands.
  • Verspaget HW; Department of Gastroenterology and Hepatology, Leiden University Medical Center, Albinusdreef 2, 2300RC Leiden, The Netherlands.
  • Geraets DT; DDL Diagnostic Laboratory, Rijswijk, The Netherlands.
  • Hommes DW; 1] Department of Gastroenterology and Hepatology, Leiden University Medical Center, Albinusdreef 2, 2300RC Leiden, The Netherlands [2] Center for Inflammatory Bowel Diseases, University of California Los Angeles Medical Center, Santa Monica, CA, USA.
  • Offerhaus GJ; Department of Pathology, Utrecht Medical Center, Utrecht, The Netherlands.
  • van den Brink GR; 1] Department of Gastroenterology and Hepatology, Leiden University Medical Center, Albinusdreef 2, 2300RC Leiden, The Netherlands [2] Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands [3] Tytgat Institute for Liver & Intestinal Research, Academic
  • Ten Dijke P; Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands.
  • Hardwick JC; Department of Gastroenterology and Hepatology, Leiden University Medical Center, Albinusdreef 2, 2300RC Leiden, The Netherlands.
Br J Cancer ; 112(1): 122-30, 2015 Jan 06.
Article em En | MEDLINE | ID: mdl-25393365
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Colon_e_reto Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Proteína Supressora de Tumor p53 / Proteínas Morfogenéticas Ósseas / Proteína Smad4 / Via de Sinalização Wnt Limite: Humans Idioma: En Revista: Br J Cancer Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Holanda
Texto completo
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Colon_e_reto Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Proteína Supressora de Tumor p53 / Proteínas Morfogenéticas Ósseas / Proteína Smad4 / Via de Sinalização Wnt Limite: Humans Idioma: En Revista: Br J Cancer Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Holanda