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Dual-specificity phosphatase 5 regulates nuclear ERK activity and suppresses skin cancer by inhibiting mutant Harvey-Ras (HRasQ61L)-driven SerpinB2 expression.
Rushworth, Linda K; Kidger, Andrew M; Delavaine, Laurent; Stewart, Graeme; van Schelven, Susanne; Davidson, Jane; Bryant, Christopher J; Caddye, Edward; East, Philip; Caunt, Christopher J; Keyse, Stephen M.
Afiliação
  • Rushworth LK; Cancer Research-UK Stress Response Laboratory, Division of Cancer Research, Medical Research Institute, Ninewells Hospital & Medical School, University of Dundee, Dundee DD1 9SY, United Kingdom;
  • Kidger AM; Cancer Research-UK Stress Response Laboratory, Division of Cancer Research, Medical Research Institute, Ninewells Hospital & Medical School, University of Dundee, Dundee DD1 9SY, United Kingdom;
  • Delavaine L; Cancer Research-UK Stress Response Laboratory, Division of Cancer Research, Medical Research Institute, Ninewells Hospital & Medical School, University of Dundee, Dundee DD1 9SY, United Kingdom;
  • Stewart G; Cancer Research-UK Stress Response Laboratory, Division of Cancer Research, Medical Research Institute, Ninewells Hospital & Medical School, University of Dundee, Dundee DD1 9SY, United Kingdom;
  • van Schelven S; Cancer Research-UK Stress Response Laboratory, Division of Cancer Research, Medical Research Institute, Ninewells Hospital & Medical School, University of Dundee, Dundee DD1 9SY, United Kingdom;
  • Davidson J; Cancer Research-UK Stress Response Laboratory, Division of Cancer Research, Medical Research Institute, Ninewells Hospital & Medical School, University of Dundee, Dundee DD1 9SY, United Kingdom;
  • Bryant CJ; Department of Biology and Biochemistry, University of Bath, Claverton Down, Bath BA2 7AY, United Kingdom; and.
  • Caddye E; Department of Biology and Biochemistry, University of Bath, Claverton Down, Bath BA2 7AY, United Kingdom; and.
  • East P; Bioinformatics and Biostatistics Group, Cancer Research-UK London Research Institute, London WC2A 3LY, United Kingdom.
  • Caunt CJ; Department of Biology and Biochemistry, University of Bath, Claverton Down, Bath BA2 7AY, United Kingdom; and.
  • Keyse SM; Cancer Research-UK Stress Response Laboratory, Division of Cancer Research, Medical Research Institute, Ninewells Hospital & Medical School, University of Dundee, Dundee DD1 9SY, United Kingdom; s.m.keyse@dundee.ac.uk.
Proc Natl Acad Sci U S A ; 111(51): 18267-72, 2014 Dec 23.
Article em En | MEDLINE | ID: mdl-25489104
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Pele Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Núcleo Celular / Genes ras / Inibidor 2 de Ativador de Plasminogênio / MAP Quinases Reguladas por Sinal Extracelular / Fosfatases de Especificidade Dupla Limite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Pele Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Núcleo Celular / Genes ras / Inibidor 2 de Ativador de Plasminogênio / MAP Quinases Reguladas por Sinal Extracelular / Fosfatases de Especificidade Dupla Limite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2014 Tipo de documento: Article