Environmental, lifestyle, and anthropometric risk factors for differentiated thyroid cancer in cuba: a case-control study.
Eur Thyroid J
; 3(3): 189-96, 2014 Sep.
Article
em En
| MEDLINE
| ID: mdl-25538901
ABSTRACT
BACKGROUND:
The incidence of differentiated thyroid carcinoma (DTC) is low in people of African origin and higher in populations living on islands, but there is no well-established explanation for these differences. Cuba is a multiethnic nation with people of African and Spanish descent. Until now, no study on the risk factors of DTC has focused on the Cuban population. Our aim is to establish the role of environmental and lifestyle factors and to relate anthropometric measurements to the risk of developing DTC in Cuba.METHODS:
We performed a case-control study of 203 DTC patients treated in two hospitals in Havana and 212 controls living in the area covered by these hospitals (i.e. parts of Havana and the municipality of Jaruco). Risk factors were analyzed using conditional logistic regression.RESULTS:
As has been shown by other studies, we found that non-African ethnicity, never smoking, parity, and high body mass index are risk factors significantly associated with DTC, whereas a history of exposure to ionizing radiation and level of education were not significantly related with disease development. Being rhesus factor-positive, having a personal history of benign thyroid disorder, agricultural occupation, and consumption of artesian well water were also associated with a significantly increased risk of developing DTC.CONCLUSIONS:
The original findings reported here concern the risk of DTC that was associated with non-African ethnicity, positive rhesus factor, farming, and drinking water from an artesian well.
Texto completo:
1
Coleções:
01-internacional
Temas:
Geral
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Tipos_de_cancer
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Outros_tipos
Base de dados:
MEDLINE
Tipo de estudo:
Etiology_studies
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Observational_studies
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Risk_factors_studies
País/Região como assunto:
Cuba
Idioma:
En
Revista:
Eur Thyroid J
Ano de publicação:
2014
Tipo de documento:
Article
País de afiliação:
Cuba