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Dual inhibition of HDAC and EGFR signaling with CUDC-101 induces potent suppression of tumor growth and metastasis in anaplastic thyroid cancer.
Zhang, Lisa; Zhang, Yaqin; Mehta, Amit; Boufraqech, Myriem; Davis, Sean; Wang, Jing; Tian, Ze; Yu, Zhiya; Boxer, Matthew B; Kiefer, Jeffrey A; Copland, John A; Smallridge, Robert C; Li, Zhuyin; Shen, Min; Kebebew, Electron.
Afiliação
  • Zhang L; Endocrine Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
  • Zhang Y; Division of Pre-Clinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD, USA.
  • Mehta A; Endocrine Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
  • Boufraqech M; Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
  • Davis S; Endocrine Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
  • Wang J; Cancer Genetics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
  • Tian Z; Curis Inc., Translational Science, Lexington, MA, USA.
  • Yu Z; Curis Inc., Translational Science, Lexington, MA, USA.
  • Boxer MB; Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
  • Kiefer JA; Division of Pre-Clinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD, USA.
  • Copland JA; Division of Information Sciences, Translational Genomics Research Institute, Phoenix, AZ, USA.
  • Smallridge RC; Department of Cancer Biology, Mayo Clinic, Jacksonville, FL, USA.
  • Li Z; Department of Cancer Biology, Mayo Clinic, Jacksonville, FL, USA.
  • Shen M; Endocrinology Division, Internal Medicine Department, Mayo Clinic, Jacksonville, FL, USA.
  • Kebebew E; Division of Pre-Clinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD, USA.
Oncotarget ; 6(11): 9073-85, 2015 Apr 20.
Article em En | MEDLINE | ID: mdl-25940539
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Quinazolinas / Neoplasias da Glândula Tireoide / Carcinoma / Inibidores de Proteínas Quinases / Inibidores de Histona Desacetilases / Terapia de Alvo Molecular / Ácidos Hidroxâmicos / Proteínas de Neoplasias / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Oncotarget Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Quinazolinas / Neoplasias da Glândula Tireoide / Carcinoma / Inibidores de Proteínas Quinases / Inibidores de Histona Desacetilases / Terapia de Alvo Molecular / Ácidos Hidroxâmicos / Proteínas de Neoplasias / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Oncotarget Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos