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Glycosaminoglycan and versican deposits in taxane-induced sclerosis.
Okada, K; Endo, Y; Miyachi, Y; Koike, Y; Kuwatsuka, Y; Utani, A.
Afiliação
  • Okada K; Department of Dermatology, Graduate School of Medicine, Kyoto University, Kyoto, 606-8507, Japan.
  • Endo Y; Department of Dermatology, Graduate School of Medicine, Kyoto University, Kyoto, 606-8507, Japan.
  • Miyachi Y; Department of Dermatology, Graduate School of Medicine, Kyoto University, Kyoto, 606-8507, Japan.
  • Koike Y; Department of Dermatology, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
  • Kuwatsuka Y; Department of Dermatology, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
  • Utani A; Department of Dermatology, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Br J Dermatol ; 173(4): 1054-8, 2015 Oct.
Article em En | MEDLINE | ID: mdl-25973640
ABSTRACT
Docetaxel and paclitaxel are widely used in the treatment of various malignant neoplasms. Taxane-induced sclerosis is dose-dependent and usually not generalized. Little information on the pathogenesis of scleroderma is currently available. Here, we report a case of generalized scleroderma and a case of early-stage oedematous sclerosis, both of which presented with intense versican deposits after administration of taxane for angiosarcoma.
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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Couro Cabeludo / Esclerodermia Localizada / Taxoides / Versicanas / Glicosaminoglicanos Limite: Humans / Male / Middle aged Idioma: En Revista: Br J Dermatol Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Japão
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Couro Cabeludo / Esclerodermia Localizada / Taxoides / Versicanas / Glicosaminoglicanos Limite: Humans / Male / Middle aged Idioma: En Revista: Br J Dermatol Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Japão