Self-aligning subatmospheric hybrid liquid junction electrospray interface for capillary electrophoresis.
Electrophoresis
; 37(3): 414-7, 2016 Feb.
Article
em En
| MEDLINE
| ID: mdl-26331678
ABSTRACT
We report a construction of a self-aligning subatmospheric hybrid liquid junction electrospray interface for CE eliminating the need for manual adjustment by guiding the capillaries in a microfabricated liquid junction glass chip at a defined angle. Both the ESI and separation capillaries are inserted into the microfabricated part until their ends touch. The distance between the capillary openings is defined by the angle between the capillaries. The microfabricated part contains channels for placement of the capillaries and connection of the external electrode reservoirs. It was fabricated using standard photolithographic/wet chemical etching techniques followed by thermal bonding. The liquid junction is connected to a subatmospheric electrospray chamber inducing the flow inside the ESI needle and helping the ion transport via aerodynamic focusing.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Temas:
Geral
Base de dados:
MEDLINE
Assunto principal:
Eletroforese Capilar
/
Espectrometria de Massas por Ionização por Electrospray
Idioma:
En
Revista:
Electrophoresis
Ano de publicação:
2016
Tipo de documento:
Article
País de afiliação:
República Tcheca