BDMC-A, an analog of curcumin, inhibits markers of invasion, angiogenesis, and metastasis in breast cancer cells via NF-&#954;B pathway--A comparative study with curcumin.

Mohankumar, Kumaravel; Sridharan, Subhashree; Pajaniradje, Sankar; Singh, Vivek Kumar; Ronsard, Larance; Banerjea, Akhil C; Somasundaram, Dinesh Babu; Coumar, Mohane Selvaraj; Periyasamy, Latha; Rajagopalan, Rukkumani

BDMC-A, an analog of curcumin, inhibits markers of invasion, angiogenesis, and metastasis in breast cancer cells via NF-κB pathway--A comparative study with curcumin.

Mohankumar, Kumaravel; Sridharan, Subhashree; Pajaniradje, Sankar; Singh, Vivek Kumar; Ronsard, Larance; Banerjea, Akhil C; Somasundaram, Dinesh Babu; Coumar, Mohane Selvaraj; Periyasamy, Latha; Rajagopalan, Rukkumani.

Afiliação

Mohankumar K; Department of Biochemistry and Molecular Biology, School of Life Sciences, Pondicherry University, Puducherry 605 014, India.
Sridharan S; Department of Biochemistry and Molecular Biology, School of Life Sciences, Pondicherry University, Puducherry 605 014, India.
Pajaniradje S; Department of Biochemistry and Molecular Biology, School of Life Sciences, Pondicherry University, Puducherry 605 014, India.
Singh VK; Centre for Bioinformatics, School of Life Sciences, Pondicherry University, Puducherry 605 014, India.
Ronsard L; Virology Laboratory-II, National Institute of Immunology, New Delhi, India.
Banerjea AC; Virology Laboratory-II, National Institute of Immunology, New Delhi, India.
Somasundaram DB; Department of Endocrinology, Dr. ALM PG Institute of Basic Medical Sciences, University of Madras, Chennai 600 013, India.
Coumar MS; Centre for Bioinformatics, School of Life Sciences, Pondicherry University, Puducherry 605 014, India.
Periyasamy L; Department of Biochemistry and Molecular Biology, School of Life Sciences, Pondicherry University, Puducherry 605 014, India.
Rajagopalan R; Department of Biochemistry and Molecular Biology, School of Life Sciences, Pondicherry University, Puducherry 605 014, India; Department of Biotechnology, University of Madras, Guindy Campus, Chennai, Tamilnadu 600025, India. Electronic address: ruks2k2@yahoo.co.in.

Biomed Pharmacother ; 74: 178-86, 2015 Aug.

Article em En | MEDLINE | ID: mdl-26349982

Assuntos

Anticarcinógenos/farmacologia; Neoplasias da Mama/tratamento farmacológico; Curcumina/análogos & derivados; Neovascularização Patológica/tratamento farmacológico; Neoplasias da Mama/irrigação sanguínea; Neoplasias da Mama/patologia; Simulação por Computador; Curcumina/farmacologia; Feminino; Humanos; Células MCF-7; Simulação de Acoplamento Molecular; NF-kappa B/metabolismo; Invasividade Neoplásica/prevenção & controle; Metástase Neoplásica/prevenção & controle; Neovascularização Patológica/patologia; Transdução de Sinais/efeitos dos fármacos

Palavras-chave

BDMC-A; Curcumin; MCF-7; Metastasis; NF-κB docking; Western blotting

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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Anticarcinógenos / Curcumina / Neovascularização Patológica Tipo de estudo: Prognostic_studies Limite: Female / Humans Idioma: En Revista: Biomed Pharmacother Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Índia

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