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Novel angiogenin mutants with increased cytotoxicity enhance the depletion of pro-inflammatory macrophages and leukemia cells ex vivo.
Cremer, Christian; Braun, Hanna; Mladenov, Radoslav; Schenke, Lea; Cong, Xiaojing; Jost, Edgar; Brümmendorf, Tim H; Fischer, Rainer; Carloni, Paolo; Barth, Stefan; Nachreiner, Thomas.
Afiliação
  • Cremer C; Department of Experimental Medicine and Immunotherapy, Institute for Applied Medical Engineering, University Hospital RWTH Aachen, Pauwelsstr. 20, 52074, Aachen, Germany.
  • Braun H; Department of Experimental Medicine and Immunotherapy, Institute for Applied Medical Engineering, University Hospital RWTH Aachen, Pauwelsstr. 20, 52074, Aachen, Germany.
  • Mladenov R; Department of Pharmaceutical Product Development, Fraunhofer Institute for Molecular Biology and Applied Ecology, Forckenbeckstr. 6, 52074, Aachen, Germany.
  • Schenke L; Department of Experimental Medicine and Immunotherapy, Institute for Applied Medical Engineering, University Hospital RWTH Aachen, Pauwelsstr. 20, 52074, Aachen, Germany.
  • Cong X; Department of Computational Biophysics, German Research School for Simulation Sciences (Joint Venture of RWTH Aachen University and Forschungszentrum Jülich), 52428, Jülich, Germany.
  • Jost E; Institute for Advanced Simulations IAS-5, Computational Biomedicine, Forschungszentrum, Jülich, Germany.
  • Brümmendorf TH; Department of Hematology and Oncology (Internal Medicine IV), University Hospital RWTH Aachen, Pauwelsstr. 30, 52074, Aachen, Germany.
  • Fischer R; Department of Hematology and Oncology (Internal Medicine IV), University Hospital RWTH Aachen, Pauwelsstr. 30, 52074, Aachen, Germany.
  • Carloni P; Department of Pharmaceutical Product Development, Fraunhofer Institute for Molecular Biology and Applied Ecology, Forckenbeckstr. 6, 52074, Aachen, Germany.
  • Barth S; Institute for Molecular Biotechnology, RWTH Aachen University, Worringer Weg 1, 52074, Aachen, Germany.
  • Nachreiner T; Department of Computational Biophysics, German Research School for Simulation Sciences (Joint Venture of RWTH Aachen University and Forschungszentrum Jülich), 52428, Jülich, Germany.
Cancer Immunol Immunother ; 64(12): 1575-86, 2015 Dec.
Article em En | MEDLINE | ID: mdl-26472728
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Leucemia / Tratamento Base de dados: MEDLINE Assunto principal: Ribonuclease Pancreático / Leucemia / Macrófagos Limite: Humans Idioma: En Revista: Cancer Immunol Immunother Assunto da revista: ALERGIA E IMUNOLOGIA / NEOPLASIAS / TERAPEUTICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Alemanha
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Leucemia / Tratamento Base de dados: MEDLINE Assunto principal: Ribonuclease Pancreático / Leucemia / Macrófagos Limite: Humans Idioma: En Revista: Cancer Immunol Immunother Assunto da revista: ALERGIA E IMUNOLOGIA / NEOPLASIAS / TERAPEUTICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Alemanha