Premedication and Chemotherapy Agents do not Impair Imgatuzumab (GA201)-Mediated Antibody-Dependent Cellular Cytotoxicity and Combination Therapies Enhance Efficacy.

Gonzalez-Nicolini, Valeria; Herter, Sylvia; Lang, Sabine; Waldhauer, Inja; Bacac, Marina; Roemmele, Michaela; Bommer, Esther; Freytag, Olivier; van Puijenbroek, Erwin; Umaña, Pablo; Gerdes, Christian A

Gonzalez-Nicolini, Valeria; Herter, Sylvia; Lang, Sabine; Waldhauer, Inja; Bacac, Marina; Roemmele, Michaela; Bommer, Esther; Freytag, Olivier; van Puijenbroek, Erwin; Umaña, Pablo; Gerdes, Christian A.

Afiliação

Gonzalez-Nicolini V; Pharma Research and Early Development, Roche Innovation Center Zurich, Schlieren, Switzerland.
Herter S; Pharma Research and Early Development, Roche Innovation Center Zurich, Schlieren, Switzerland.
Lang S; Pharma Research and Early Development, Roche Innovation Center Zurich, Schlieren, Switzerland.
Waldhauer I; Pharma Research and Early Development, Roche Innovation Center Zurich, Schlieren, Switzerland.
Bacac M; Pharma Research and Early Development, Roche Innovation Center Zurich, Schlieren, Switzerland.
Roemmele M; Pharma Research and Early Development, Roche Innovation Center Zurich, Schlieren, Switzerland.
Bommer E; Pharma Research and Early Development, Roche Innovation Center Zurich, Schlieren, Switzerland.
Freytag O; Pharma Research and Early Development, Roche Innovation Center Zurich, Schlieren, Switzerland.
van Puijenbroek E; Pharma Research and Early Development, Roche Innovation Center Zurich, Schlieren, Switzerland.
Umaña P; Pharma Research and Early Development, Roche Innovation Center Zurich, Schlieren, Switzerland.
Gerdes CA; Pharma Research and Early Development, Roche Innovation Center Zurich, Schlieren, Switzerland. christian.gerdes@roche.com.

Clin Cancer Res ; 22(10): 2453-61, 2016 05 15.

Article em En | MEDLINE | ID: mdl-26581243

Assuntos

Anticorpos Monoclonais/uso terapêutico; Citotoxicidade Celular Dependente de Anticorpos/efeitos dos fármacos; Antineoplásicos/uso terapêutico; Células A549; Linhagem Celular Tumoral; Cetuximab/uso terapêutico; Terapia Combinada/métodos; Receptores ErbB/antagonistas & inibidores; Células HT29; Humanos; Leucócitos Mononucleares/efeitos dos fármacos; Leucócitos Mononucleares/metabolismo

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Anticorpos Monoclonais / Citotoxicidade Celular Dependente de Anticorpos / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Clin Cancer Res Assunto da revista: NEOPLASIAS Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Suíça

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