Lowering Endogenous Cathepsin D Abundance Results in Reactive Oxygen Species Accumulation and Cell Senescence.

Su, Siyuan; Zhu, Xu; Lin, Liang; Chen, Xianwei; Wang, Yang; Zi, Jin; Dong, Yusheng; Xie, Yingying; Zhu, Yinghui; Zhang, Ju; Zhu, Jianhui; Xu, Dan; Xu, Ningzhi; Lou, Xiaomin; Liu, Siqi

Su, Siyuan; Zhu, Xu; Lin, Liang; Chen, Xianwei; Wang, Yang; Zi, Jin; Dong, Yusheng; Xie, Yingying; Zhu, Yinghui; Zhang, Ju; Zhu, Jianhui; Xu, Dan; Xu, Ningzhi; Lou, Xiaomin; Liu, Siqi.

Afiliação

Su S; From the CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China, 100101.
Zhu X; §University of Chinese Academy of Sciences, Beijing, China, 100049.
Lin L; From the CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China, 100101.
Chen X; ¶Proteomics Division, BGI-Shenzhen, Shenzhen, Guangdong, China, 518083.
Wang Y; From the CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China, 100101.
Zi J; §University of Chinese Academy of Sciences, Beijing, China, 100049.
Dong Y; From the CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China, 100101.
Xie Y; §University of Chinese Academy of Sciences, Beijing, China, 100049.
Zhu Y; ¶Proteomics Division, BGI-Shenzhen, Shenzhen, Guangdong, China, 518083.
Zhang J; âBeijing Protein Innovation, Beijing, China, 101318.
Zhu J; From the CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China, 100101.
Xu D; §University of Chinese Academy of Sciences, Beijing, China, 100049.
Xu N; From the CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China, 100101.
Lou X; §University of Chinese Academy of Sciences, Beijing, China, 100049.
Liu S; From the CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China, 100101.

Mol Cell Proteomics ; 16(7): 1217-1232, 2017 07.

Article em En | MEDLINE | ID: mdl-26657266

Assuntos

Catepsina D/genética; Fator 2 Relacionado a NF-E2/metabolismo; Neoplasias/metabolismo; Proteômica/métodos; Espécies Reativas de Oxigênio/metabolismo; Células A549; Animais; Catepsina D/metabolismo; Núcleo Celular/genética; Núcleo Celular/metabolismo; Proliferação de Células; Senescência Celular; Regulação para Baixo; Feminino; Técnicas de Silenciamento de Genes; Células HeLa; Humanos; Lisossomos/genética; Lisossomos/metabolismo; Camundongos; Transplante de Neoplasias; Neoplasias/genética; Estresse Oxidativo

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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Catepsina D / Espécies Reativas de Oxigênio / Proteômica / Fator 2 Relacionado a NF-E2 / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Mol Cell Proteomics Assunto da revista: BIOLOGIA MOLECULAR / BIOQUIMICA Ano de publicação: 2017 Tipo de documento: Article

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