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Multikinase Inhibitors Induce Cutaneous Toxicity through OAT6-Mediated Uptake and MAP3K7-Driven Cell Death.
Zimmerman, Eric I; Gibson, Alice A; Hu, Shuiying; Vasilyeva, Aksana; Orwick, Shelley J; Du, Guoqing; Mascara, Gerard P; Ong, Su Sien; Chen, Taosheng; Vogel, Peter; Inaba, Hiroto; Maitland, Michael L; Sparreboom, Alex; Baker, Sharyn D.
Afiliação
  • Zimmerman EI; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee.
  • Gibson AA; Division of Pharmaceutics, College of Pharmacy & Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio.
  • Hu S; Division of Pharmaceutics, College of Pharmacy & Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio.
  • Vasilyeva A; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee.
  • Orwick SJ; Division of Pharmaceutics, College of Pharmacy & Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio.
  • Du G; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee.
  • Mascara GP; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee.
  • Ong SS; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee.
  • Chen T; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee.
  • Vogel P; Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee.
  • Inaba H; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee.
  • Maitland ML; Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, Illinois.
  • Sparreboom A; Division of Pharmaceutics, College of Pharmacy & Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio.
  • Baker SD; Division of Pharmaceutics, College of Pharmacy & Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio. baker.2480@osu.edu.
Cancer Res ; 76(1): 117-26, 2016 Jan 01.
Article em En | MEDLINE | ID: mdl-26677977
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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Compostos de Fenilureia / Dermatopatias / Niacinamida / MAP Quinase Quinase Quinases / Transportadores de Ânions Orgânicos / Inibidores de Proteínas Quinases Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Cancer Res Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Compostos de Fenilureia / Dermatopatias / Niacinamida / MAP Quinase Quinase Quinases / Transportadores de Ânions Orgânicos / Inibidores de Proteínas Quinases Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Cancer Res Ano de publicação: 2016 Tipo de documento: Article