Discovery of new methylation markers to improve screening for cervical intraepithelial neoplasia grade 2/3.

Boers, A; Wang, R; van Leeuwen, R W; Klip, H G; de Bock, G H; Hollema, H; van Criekinge, W; de Meyer, T; Denil, S; van der Zee, A G J; Schuuring, E; Wisman, G B A

Boers, A; Wang, R; van Leeuwen, R W; Klip, H G; de Bock, G H; Hollema, H; van Criekinge, W; de Meyer, T; Denil, S; van der Zee, A G J; Schuuring, E; Wisman, G B A.

Afiliação

Boers A; Department of Gynecologic Oncology, internal postal code DA13, Cancer Reserch Center Groningen, University of Groningen, University Medical Center Groningen, PO box 30.001, 9700 RB Groningen, The Netherlands.
Wang R; Department of Gynecologic Oncology, internal postal code DA13, Cancer Reserch Center Groningen, University of Groningen, University Medical Center Groningen, PO box 30.001, 9700 RB Groningen, The Netherlands.
van Leeuwen RW; Department of Gynecologic Oncology, internal postal code DA13, Cancer Reserch Center Groningen, University of Groningen, University Medical Center Groningen, PO box 30.001, 9700 RB Groningen, The Netherlands.
Klip HG; Department of Gynecologic Oncology, internal postal code DA13, Cancer Reserch Center Groningen, University of Groningen, University Medical Center Groningen, PO box 30.001, 9700 RB Groningen, The Netherlands.
de Bock GH; Department of Epidemiology, Cancer Reserch Center Groningen, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Hollema H; Department of Pathology, Cancer Reserch Center Groningen, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
van Criekinge W; Department of Mathematical Modeling, Statistics and Bioinformatics, Ghent University, Ghent, Belgium.
de Meyer T; Department of Mathematical Modeling, Statistics and Bioinformatics, Ghent University, Ghent, Belgium.
Denil S; Department of Mathematical Modeling, Statistics and Bioinformatics, Ghent University, Ghent, Belgium.
van der Zee AGJ; Department of Gynecologic Oncology, internal postal code DA13, Cancer Reserch Center Groningen, University of Groningen, University Medical Center Groningen, PO box 30.001, 9700 RB Groningen, The Netherlands.
Schuuring E; Department of Pathology, Cancer Reserch Center Groningen, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Wisman GBA; Department of Gynecologic Oncology, internal postal code DA13, Cancer Reserch Center Groningen, University of Groningen, University Medical Center Groningen, PO box 30.001, 9700 RB Groningen, The Netherlands.

Clin Epigenetics ; 8: 29, 2016.

Article em En | MEDLINE | ID: mdl-26962367

Assuntos

Displasia do Colo do Útero/diagnóstico; Neoplasias do Colo do Útero/diagnóstico; Adulto; Estudos de Casos e Controles; Colo do Útero/patologia; Metilação de DNA/genética; Feminino; Genes Neoplásicos/genética; Marcadores Genéticos; Estudo de Associação Genômica Ampla; Humanos; Teste de Papanicolaou; Reação em Cadeia da Polimerase/métodos; Sensibilidade e Especificidade; Neoplasias do Colo do Útero/genética; Neoplasias do Colo do Útero/patologia; Displasia do Colo do Útero/genética; Displasia do Colo do Útero/patologia

Palavras-chave

Cervical cancer screening; Cervical precancerous lesions; Cervical scraping; DNA methylation; Human papillomavirus (HPV); MethylCap-seq; Quantitative methylation-specific PCR (QMSP)

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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Saude_da_mulher / Colo_do_utero / Tipos_de_cancer / Colo_do_utero / Outros_tipos Base de dados: MEDLINE Assunto principal: Displasia do Colo do Útero / Neoplasias do Colo do Útero Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Limite: Adult / Female / Humans Idioma: En Revista: Clin Epigenetics Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Holanda

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