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Discovery of a specific inhibitor of human GLUT5 by virtual screening and in vitro transport evaluation.
George Thompson, Alayna M; Ursu, Oleg; Babkin, Petr; Iancu, Cristina V; Whang, Alex; Oprea, Tudor I; Choe, Jun-yong.
Afiliação
  • George Thompson AM; Department of Biochemistry and Molecular Biology, Rosalind Franklin University of Medicine and Science, The Chicago Medical School, 3333 Green Bay Road, North Chicago, IL, 60064, USA.
  • Ursu O; Department of Internal Medicine, Translational Informatics Division, MSC09 5025, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA.
  • Babkin P; Department of Biochemistry and Molecular Biology, Rosalind Franklin University of Medicine and Science, The Chicago Medical School, 3333 Green Bay Road, North Chicago, IL, 60064, USA.
  • Iancu CV; Department of Biochemistry and Molecular Biology, Rosalind Franklin University of Medicine and Science, The Chicago Medical School, 3333 Green Bay Road, North Chicago, IL, 60064, USA.
  • Whang A; Department of Biochemistry and Molecular Biology, Rosalind Franklin University of Medicine and Science, The Chicago Medical School, 3333 Green Bay Road, North Chicago, IL, 60064, USA.
  • Oprea TI; Department of Internal Medicine, Translational Informatics Division, MSC09 5025, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA.
  • Choe JY; Department of Biochemistry and Molecular Biology, Rosalind Franklin University of Medicine and Science, The Chicago Medical School, 3333 Green Bay Road, North Chicago, IL, 60064, USA.
Sci Rep ; 6: 24240, 2016 Apr 14.
Article em En | MEDLINE | ID: mdl-27074918

Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Avaliação Pré-Clínica de Medicamentos / Inibidores Enzimáticos / Transportador de Glucose Tipo 5 Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Humans Idioma: En Revista: Sci Rep Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Avaliação Pré-Clínica de Medicamentos / Inibidores Enzimáticos / Transportador de Glucose Tipo 5 Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Humans Idioma: En Revista: Sci Rep Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos