Structural Basis for p53 Lys120-Acetylation-Dependent DNA-Binding Mode.

Vainer, Radion; Cohen, Sarit; Shahar, Anat; Zarivach, Raz; Arbely, Eyal

Vainer, Radion; Cohen, Sarit; Shahar, Anat; Zarivach, Raz; Arbely, Eyal.

Afiliação

Vainer R; Department of Chemistry, Ben-Gurion University of the Negev, Beer-Sheva, 84105, Israel.
Cohen S; Department of Chemistry, Ben-Gurion University of the Negev, Beer-Sheva, 84105, Israel; The National Institute for Biotechnology in the Negev, Ben-Gurion University of the Negev, Beer-Sheva, 84105, Israel.
Shahar A; The National Institute for Biotechnology in the Negev, Ben-Gurion University of the Negev, Beer-Sheva, 84105, Israel.
Zarivach R; Department of Life-Sciences, Ben-Gurion University of the Negev, Beer-Sheva, 84105, Israel; The National Institute for Biotechnology in the Negev, Ben-Gurion University of the Negev, Beer-Sheva, 84105, Israel.
Arbely E; Department of Chemistry, Ben-Gurion University of the Negev, Beer-Sheva, 84105, Israel; The National Institute for Biotechnology in the Negev, Ben-Gurion University of the Negev, Beer-Sheva, 84105, Israel; Department of Life-Sciences, Ben-Gurion University of the Negev, Beer-Sheva, 84105, Israel. El

J Mol Biol ; 428(15): 3013-25, 2016 07 31.

Article em En | MEDLINE | ID: mdl-27338200

Assuntos

Proteínas de Ligação a DNA/metabolismo; DNA/metabolismo; Proteína Supressora de Tumor p53/metabolismo; Acetilação; Sítios de Ligação/genética; Modelos Moleculares; Conformação Molecular; Ligação Proteica/genética; Elementos de Resposta/genética

Palavras-chave

Hoogsteen base pairing; apoptosis; genetic code expansion; lysine acetylation; transcription

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: DNA / Proteína Supressora de Tumor p53 / Proteínas de Ligação a DNA Tipo de estudo: Prognostic_studies Idioma: En Revista: J Mol Biol Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Israel

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