Advances in genetics: widening our understanding of prostate cancer.
F1000Res
; 52016.
Article
em En
| MEDLINE
| ID: mdl-27408704
ABSTRACT
Prostate cancer is a leading cause of cancer-related death in Western men. Our understanding of the genetic alterations associated with disease predisposition, development, progression, and therapy response is rapidly improving, at least in part, owing to the development of next-generation sequencing technologies. Large advances have been made in our understanding of the genetics of prostate cancer through the application of whole-exome sequencing, and this review summarises recent advances in this field and discusses how exome sequencing could be used clinically to promote personalised medicine for prostate cancer patients.
Texto completo:
1
Coleções:
01-internacional
Temas:
Geral
/
Tipos_de_cancer
/
Prostata
Base de dados:
MEDLINE
Idioma:
En
Revista:
F1000Res
Ano de publicação:
2016
Tipo de documento:
Article
País de afiliação:
Reino Unido