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Ercc1 Deficiency Promotes Tumorigenesis and Increases Cisplatin Sensitivity in a Tp53 Context-Specific Manner.
Jokic, Mladen; Vlasic, Ignacija; Rinneburger, Miriam; Klümper, Niklas; Spiro, Judith; Vogel, Wenzel; Offermann, Anne; Kümpers, Christiane; Fritz, Christian; Schmitt, Anna; Riabinska, Arina; Wittersheim, Maike; Michels, Sebastian; Ozretic, Luka; Florin, Alexandra; Welcker, Daniela; Akyuz, Mehmet Deniz; Nowak, Michael; Erkel, Martin; Wolf, Jürgen; Büttner, Reinhard; Schumacher, Björn; Thomale, Jürgen; Persigehl, Thorsten; Maintz, David; Perner, Sven; Reinhardt, Hans Christian.
Afiliação
  • Jokic M; Department I of Internal Medicine, University Hospital of Cologne, Weyertal 115B, 50931, Cologne, Germany. mladen.jokic@uk-koeln.de.
  • Vlasic I; Cologne Excellence Cluster on Cellular Stress Response in Aging-Associated Diseases, University of Cologne, Weyertal 115B, 50931, Cologne, Germany.
  • Rinneburger M; Department I of Internal Medicine, University Hospital of Cologne, Weyertal 115B, 50931, Cologne, Germany.
  • Klümper N; Cologne Excellence Cluster on Cellular Stress Response in Aging-Associated Diseases, University of Cologne, Weyertal 115B, 50931, Cologne, Germany.
  • Spiro J; Department I of Internal Medicine, University Hospital of Cologne, Weyertal 115B, 50931, Cologne, Germany.
  • Vogel W; Cologne Excellence Cluster on Cellular Stress Response in Aging-Associated Diseases, University of Cologne, Weyertal 115B, 50931, Cologne, Germany.
  • Offermann A; Pathology of the University Medical Center Schleswig-Holstein, Campus Luebeck and the Research Center Borstel, Leibniz Center for Medicine and Biosciences, 23538 Luebeck and 23845 Borstel, Germany.
  • Kümpers C; Department of Radiology, University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
  • Fritz C; Pathology of the University Medical Center Schleswig-Holstein, Campus Luebeck and the Research Center Borstel, Leibniz Center for Medicine and Biosciences, 23538 Luebeck and 23845 Borstel, Germany.
  • Schmitt A; Pathology of the University Medical Center Schleswig-Holstein, Campus Luebeck and the Research Center Borstel, Leibniz Center for Medicine and Biosciences, 23538 Luebeck and 23845 Borstel, Germany.
  • Riabinska A; Pathology of the University Medical Center Schleswig-Holstein, Campus Luebeck and the Research Center Borstel, Leibniz Center for Medicine and Biosciences, 23538 Luebeck and 23845 Borstel, Germany.
  • Wittersheim M; Department I of Internal Medicine, University Hospital of Cologne, Weyertal 115B, 50931, Cologne, Germany.
  • Michels S; Cologne Excellence Cluster on Cellular Stress Response in Aging-Associated Diseases, University of Cologne, Weyertal 115B, 50931, Cologne, Germany.
  • Ozretic L; Department I of Internal Medicine, University Hospital of Cologne, Weyertal 115B, 50931, Cologne, Germany.
  • Florin A; Cologne Excellence Cluster on Cellular Stress Response in Aging-Associated Diseases, University of Cologne, Weyertal 115B, 50931, Cologne, Germany.
  • Welcker D; Department I of Internal Medicine, University Hospital of Cologne, Weyertal 115B, 50931, Cologne, Germany.
  • Akyuz MD; Cologne Excellence Cluster on Cellular Stress Response in Aging-Associated Diseases, University of Cologne, Weyertal 115B, 50931, Cologne, Germany.
  • Nowak M; Institute of Pathology, University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
  • Erkel M; Department I of Internal Medicine, University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
  • Wolf J; Institute of Pathology, University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
  • Büttner R; Institute of Pathology, University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
  • Schumacher B; Department I of Internal Medicine, University Hospital of Cologne, Weyertal 115B, 50931, Cologne, Germany.
  • Thomale J; Cologne Excellence Cluster on Cellular Stress Response in Aging-Associated Diseases, University of Cologne, Weyertal 115B, 50931, Cologne, Germany.
  • Persigehl T; Department II of Internal Medicine, University Hospital Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
  • Maintz D; Institute for genome stability in ageing and disease, CECAD Research Center, Joseph-Stelzmann-Str. 26, 50931, Cologne, Germany.
  • Perner S; Institute of Pathology, University Hospital Bonn, Sigmund-Freud-Str. 25, 53127, Bonn, Germany.
  • Reinhardt HC; Institute for Cell Biology, University Hospital Essen, Hufelandstraße 55, 45122, Essen, Germany.
Mol Cancer Res ; 14(11): 1110-1123, 2016 11.
Article em En | MEDLINE | ID: mdl-27514406
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Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Pulmao Base de dados: MEDLINE Assunto principal: Adenocarcinoma / Proteína Supressora de Tumor p53 / Proteínas Proto-Oncogênicas p21(ras) / Cisplatino / Proteínas de Ligação a DNA / Endonucleases / Neoplasias Pulmonares Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Mol Cancer Res Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Alemanha
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Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Pulmao Base de dados: MEDLINE Assunto principal: Adenocarcinoma / Proteína Supressora de Tumor p53 / Proteínas Proto-Oncogênicas p21(ras) / Cisplatino / Proteínas de Ligação a DNA / Endonucleases / Neoplasias Pulmonares Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Mol Cancer Res Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Alemanha