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Low-dose Actinomycin-D treatment re-establishes the tumoursuppressive function of P53 in RELA-positive ependymoma.
Tzaridis, Theophilos; Milde, Till; Pajtler, Kristian W; Bender, Sebastian; Jones, David T W; Müller, Simone; Wittmann, Andrea; Schlotter, Magdalena; Kulozik, Andreas E; Lichter, Peter; Peter Collins, V; Witt, Olaf; Kool, Marcel; Korshunov, Andrey; Pfister, Stefan M; Witt, Hendrik.
Afiliação
  • Tzaridis T; Division of Pediatric Neurooncology (B062), German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Milde T; Department of Pediatric Oncology, Hematology and Immunology, Children's Hospital, University of Heidelberg, Heidelberg, Germany.
  • Pajtler KW; Clinical Cooperation Unit Pediatric Oncology (G340), German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Bender S; National Center for Tumor diseases (NCT), Clinical Trial Center, Heidelberg, Germany.
  • Jones DT; Division of Pediatric Neurooncology (B062), German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Müller S; Department of Pediatric Oncology, Hematology and Immunology, Children's Hospital, University of Heidelberg, Heidelberg, Germany.
  • Wittmann A; National Center for Tumor diseases (NCT), Clinical Trial Center, Heidelberg, Germany.
  • Schlotter M; Division of Pediatric Neurooncology (B062), German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Kulozik AE; Division of Pediatric Neurooncology (B062), German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Lichter P; Department of Cardiology, Angiology and Pulmology, University of Heidelberg, Heidelberg, Germany.
  • Peter Collins V; Division of Pediatric Neurooncology (B062), German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Witt O; Division of Molecular Genetics (B060), German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.
  • Kool M; Department of Pediatric Oncology, Hematology and Immunology, Children's Hospital, University of Heidelberg, Heidelberg, Germany.
  • Korshunov A; Division of Molecular Genetics (B060), German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.
  • Pfister SM; Division of Molecular Histopathology, Department of Pathology, University of Cambridge, Cambridge UK.
  • Witt H; Department of Pediatric Oncology, Hematology and Immunology, Children's Hospital, University of Heidelberg, Heidelberg, Germany.
Oncotarget ; 7(38): 61860-61873, 2016 Sep 20.
Article em En | MEDLINE | ID: mdl-27556362
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Proteína Supressora de Tumor p53 / Dactinomicina / Ependimoma / Fator de Transcrição RelA Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Oncotarget Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Alemanha
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Proteína Supressora de Tumor p53 / Dactinomicina / Ependimoma / Fator de Transcrição RelA Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Oncotarget Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Alemanha