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Ionic immune suppression within the tumour microenvironment limits T cell effector function.
Eil, Robert; Vodnala, Suman K; Clever, David; Klebanoff, Christopher A; Sukumar, Madhusudhanan; Pan, Jenny H; Palmer, Douglas C; Gros, Alena; Yamamoto, Tori N; Patel, Shashank J; Guittard, Geoffrey C; Yu, Zhiya; Carbonaro, Valentina; Okkenhaug, Klaus; Schrump, David S; Linehan, W Marston; Roychoudhuri, Rahul; Restifo, Nicholas P.
Afiliação
  • Eil R; National Cancer Institute, National Institutes of Health (NIH), Bethesda, Maryland 20892, USA.
  • Vodnala SK; National Cancer Institute, National Institutes of Health (NIH), Bethesda, Maryland 20892, USA.
  • Clever D; National Cancer Institute, National Institutes of Health (NIH), Bethesda, Maryland 20892, USA.
  • Klebanoff CA; National Cancer Institute, National Institutes of Health (NIH), Bethesda, Maryland 20892, USA.
  • Sukumar M; Center for Cell Engineering and Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
  • Pan JH; National Cancer Institute, National Institutes of Health (NIH), Bethesda, Maryland 20892, USA.
  • Palmer DC; National Cancer Institute, National Institutes of Health (NIH), Bethesda, Maryland 20892, USA.
  • Gros A; National Cancer Institute, National Institutes of Health (NIH), Bethesda, Maryland 20892, USA.
  • Yamamoto TN; National Cancer Institute, National Institutes of Health (NIH), Bethesda, Maryland 20892, USA.
  • Patel SJ; National Cancer Institute, National Institutes of Health (NIH), Bethesda, Maryland 20892, USA.
  • Guittard GC; National Cancer Institute, National Institutes of Health (NIH), Bethesda, Maryland 20892, USA.
  • Yu Z; National Cancer Institute, National Institutes of Health (NIH), Bethesda, Maryland 20892, USA.
  • Carbonaro V; National Cancer Institute, National Institutes of Health (NIH), Bethesda, Maryland 20892, USA.
  • Okkenhaug K; Laboratory of Lymphocyte Signalling and Development, The Babraham Institute, Cambridge CB22 3AT, UK.
  • Schrump DS; Laboratory of Lymphocyte Signalling and Development, The Babraham Institute, Cambridge CB22 3AT, UK.
  • Linehan WM; National Cancer Institute, National Institutes of Health (NIH), Bethesda, Maryland 20892, USA.
  • Roychoudhuri R; National Cancer Institute, National Institutes of Health (NIH), Bethesda, Maryland 20892, USA.
  • Restifo NP; Laboratory of Lymphocyte Signalling and Development, The Babraham Institute, Cambridge CB22 3AT, UK.
Nature ; 537(7621): 539-543, 2016 09 22.
Article em En | MEDLINE | ID: mdl-27626381
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Pele Base de dados: MEDLINE Assunto principal: Potássio / Linfócitos T / Cátions Monovalentes / Evasão Tumoral / Microambiente Tumoral / Melanoma Limite: Animals / Humans / Male Idioma: En Revista: Nature Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Pele Base de dados: MEDLINE Assunto principal: Potássio / Linfócitos T / Cátions Monovalentes / Evasão Tumoral / Microambiente Tumoral / Melanoma Limite: Animals / Humans / Male Idioma: En Revista: Nature Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos