Baicalein inhibits TNF-&#945;-induced NF-&#954;B activation and expression of NF-&#954;B-regulated target gene products.

Li, Junbo; Ma, Juan; Wang, Ke Si; Mi, Chunliu; Wang, Zhe; Piao, Lian Xun; Xu, Guang Hua; Li, Xuezheng; Lee, Jung Joon; Jin, Xuejun

Baicalein inhibits TNF-α-induced NF-κB activation and expression of NF-κB-regulated target gene products.

Li, Junbo; Ma, Juan; Wang, Ke Si; Mi, Chunliu; Wang, Zhe; Piao, Lian Xun; Xu, Guang Hua; Li, Xuezheng; Lee, Jung Joon; Jin, Xuejun.

Afiliação

Li J; Key Laboratory of Natural Resources of Changbai Mountain and Functional Molecules, Ministry of Education, Molecular Cancer Research Center, College of Pharmacy, Yanbian University, Yanji, Jilin 133002, P.R. China.
Ma J; Key Laboratory of Natural Resources of Changbai Mountain and Functional Molecules, Ministry of Education, Molecular Cancer Research Center, College of Pharmacy, Yanbian University, Yanji, Jilin 133002, P.R. China.
Wang KS; Key Laboratory of Natural Resources of Changbai Mountain and Functional Molecules, Ministry of Education, Molecular Cancer Research Center, College of Pharmacy, Yanbian University, Yanji, Jilin 133002, P.R. China.
Mi C; Key Laboratory of Natural Resources of Changbai Mountain and Functional Molecules, Ministry of Education, Molecular Cancer Research Center, College of Pharmacy, Yanbian University, Yanji, Jilin 133002, P.R. China.
Wang Z; Key Laboratory of Natural Resources of Changbai Mountain and Functional Molecules, Ministry of Education, Molecular Cancer Research Center, College of Pharmacy, Yanbian University, Yanji, Jilin 133002, P.R. China.
Piao LX; Key Laboratory of Natural Resources of Changbai Mountain and Functional Molecules, Ministry of Education, Molecular Cancer Research Center, College of Pharmacy, Yanbian University, Yanji, Jilin 133002, P.R. China.
Xu GH; Key Laboratory of Natural Resources of Changbai Mountain and Functional Molecules, Ministry of Education, Molecular Cancer Research Center, College of Pharmacy, Yanbian University, Yanji, Jilin 133002, P.R. China.
Li X; Key Laboratory of Natural Resources of Changbai Mountain and Functional Molecules, Ministry of Education, Molecular Cancer Research Center, College of Pharmacy, Yanbian University, Yanji, Jilin 133002, P.R. China.
Lee JJ; Key Laboratory of Natural Resources of Changbai Mountain and Functional Molecules, Ministry of Education, Molecular Cancer Research Center, College of Pharmacy, Yanbian University, Yanji, Jilin 133002, P.R. China.
Jin X; Key Laboratory of Natural Resources of Changbai Mountain and Functional Molecules, Ministry of Education, Molecular Cancer Research Center, College of Pharmacy, Yanbian University, Yanji, Jilin 133002, P.R. China.

Oncol Rep ; 36(5): 2771-2776, 2016 Nov.

Article em En | MEDLINE | ID: mdl-27667548

Assuntos

Flavanonas/administração & dosagem; Extratos Vegetais/administração & dosagem; Fator de Transcrição RelA/biossíntese; Fator de Necrose Tumoral alfa/genética; Apoptose/genética; Proliferação de Células/efeitos dos fármacos; Citometria de Fluxo; Regulação Neoplásica da Expressão Gênica/efeitos dos fármacos; Células HeLa; Humanos; Quinase I-kappa B/biossíntese; Quinase I-kappa B/genética; NF-kappa B/biossíntese; NF-kappa B/genética; Proteínas de Neoplasias/biossíntese; Proteínas de Neoplasias/genética; Fosforilação; Scutellaria baicalensis; Transdução de Sinais/efeitos dos fármacos; Fator de Transcrição RelA/genética; Proteínas Quinases p38 Ativadas por Mitógeno/biossíntese; Proteínas Quinases p38 Ativadas por Mitógeno/genética

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Extratos Vegetais / Fator de Necrose Tumoral alfa / Flavanonas / Fator de Transcrição RelA Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Oncol Rep Assunto da revista: NEOPLASIAS Ano de publicação: 2016 Tipo de documento: Article

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