Safety and Wound Outcomes Following Genetically Corrected Autologous Epidermal Grafts in Patients With Recessive Dystrophic Epidermolysis Bullosa.

Siprashvili, Zurab; Nguyen, Ngon T; Gorell, Emily S; Loutit, Kylie; Khuu, Phuong; Furukawa, Louise K; Lorenz, H Peter; Leung, Thomas H; Keene, Douglas R; Rieger, Kerri E; Khavari, Paul; Lane, Alfred T; Tang, Jean Y; Marinkovich, M Peter

Siprashvili, Zurab; Nguyen, Ngon T; Gorell, Emily S; Loutit, Kylie; Khuu, Phuong; Furukawa, Louise K; Lorenz, H Peter; Leung, Thomas H; Keene, Douglas R; Rieger, Kerri E; Khavari, Paul; Lane, Alfred T; Tang, Jean Y; Marinkovich, M Peter.

Afiliação

Siprashvili Z; Department of Dermatology, School of Medicine, Stanford University, Stanford, California.
Nguyen NT; Department of Dermatology, School of Medicine, Stanford University, Stanford, California.
Gorell ES; Department of Dermatology, School of Medicine, Stanford University, Stanford, California.
Loutit K; Department of Dermatology, School of Medicine, Stanford University, Stanford, California.
Khuu P; Department of Dermatology, School of Medicine, Stanford University, Stanford, California.
Furukawa LK; Lucile Packard Children's Hospital, Stanford University, Stanford, California.
Lorenz HP; Lucile Packard Children's Hospital, Stanford University, Stanford, California.
Leung TH; Department of Dermatology, School of Medicine, Stanford University, Stanford, California3Now with Department of Dermatology, University of Pennsylvania, Philadelphia.
Keene DR; Shriners Hospital for Children, Portland, Oregon.
Rieger KE; Department of Dermatology, School of Medicine, Stanford University, Stanford, California.
Khavari P; Department of Dermatology, School of Medicine, Stanford University, Stanford, California5Veterans Affairs Medical Center, Palo Alto, California.
Lane AT; Department of Dermatology, School of Medicine, Stanford University, Stanford, California.
Tang JY; Department of Dermatology, School of Medicine, Stanford University, Stanford, California.
Marinkovich MP; Department of Dermatology, School of Medicine, Stanford University, Stanford, California5Veterans Affairs Medical Center, Palo Alto, California.

JAMA ; 316(17): 1808-1817, 2016 Nov 01.

Article em En | MEDLINE | ID: mdl-27802546

Assuntos

Colágeno Tipo VII/genética; Epidermólise Bolhosa Distrófica/terapia; Técnicas de Transferência de Genes; Queratinócitos/transplante; Cicatrização; Adolescente; Adulto; Colágeno Tipo VII/metabolismo; Colágeno Tipo VII/uso terapêutico; Epidermólise Bolhosa Distrófica/genética; Epidermólise Bolhosa Distrófica/metabolismo; Epidermólise Bolhosa Distrófica/patologia; Humanos; Masculino; Vírus da Leucemia Murina de Moloney/genética; Pirimidinas; Proteínas Recombinantes/genética; Proteínas Recombinantes/metabolismo; Proteínas Recombinantes/uso terapêutico; Retalhos Cirúrgicos; Fatores de Tempo; Ferimentos e Lesões/metabolismo; Ferimentos e Lesões/terapia; Adulto Jovem

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Cicatrização / Queratinócitos / Epidermólise Bolhosa Distrófica / Técnicas de Transferência de Genes / Colágeno Tipo VII Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adolescent / Adult / Humans / Male Idioma: En Revista: JAMA Ano de publicação: 2016 Tipo de documento: Article

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