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The addition of ketone bodies alleviates mitochondrial dysfunction by restoring complex I assembly in a MELAS cellular model.
Frey, Samuel; Geffroy, Guillaume; Desquiret-Dumas, Valerie; Gueguen, Naig; Bris, Celine; Belal, Sophie; Amati-Bonneau, Patrizia; Chevrollier, Arnaud; Barth, Magalie; Henrion, Daniel; Lenaers, Guy; Bonneau, Dominique; Reynier, Pascal; Procaccio, Vincent.
Afiliação
  • Frey S; UMR CNRS 6214-INSERM U1083, Mitovasc Institute, Angers University, Angers, France.
  • Geffroy G; UMR CNRS 6214-INSERM U1083, Mitovasc Institute, Angers University, Angers, France.
  • Desquiret-Dumas V; UMR CNRS 6214-INSERM U1083, Mitovasc Institute, Angers University, Angers, France; Biochemistry and Genetics Department, Angers Hospital, F-49000, France.
  • Gueguen N; UMR CNRS 6214-INSERM U1083, Mitovasc Institute, Angers University, Angers, France; Biochemistry and Genetics Department, Angers Hospital, F-49000, France.
  • Bris C; UMR CNRS 6214-INSERM U1083, Mitovasc Institute, Angers University, Angers, France; Biochemistry and Genetics Department, Angers Hospital, F-49000, France.
  • Belal S; UMR CNRS 6214-INSERM U1083, Mitovasc Institute, Angers University, Angers, France.
  • Amati-Bonneau P; UMR CNRS 6214-INSERM U1083, Mitovasc Institute, Angers University, Angers, France; Biochemistry and Genetics Department, Angers Hospital, F-49000, France.
  • Chevrollier A; UMR CNRS 6214-INSERM U1083, Mitovasc Institute, Angers University, Angers, France.
  • Barth M; Biochemistry and Genetics Department, Angers Hospital, F-49000, France.
  • Henrion D; UMR CNRS 6214-INSERM U1083, Mitovasc Institute, Angers University, Angers, France.
  • Lenaers G; UMR CNRS 6214-INSERM U1083, Mitovasc Institute, Angers University, Angers, France.
  • Bonneau D; UMR CNRS 6214-INSERM U1083, Mitovasc Institute, Angers University, Angers, France; Biochemistry and Genetics Department, Angers Hospital, F-49000, France.
  • Reynier P; UMR CNRS 6214-INSERM U1083, Mitovasc Institute, Angers University, Angers, France; Biochemistry and Genetics Department, Angers Hospital, F-49000, France.
  • Procaccio V; UMR CNRS 6214-INSERM U1083, Mitovasc Institute, Angers University, Angers, France; Biochemistry and Genetics Department, Angers Hospital, F-49000, France. Electronic address: ViProcaccio@chu-angers.fr.
Biochim Biophys Acta Mol Basis Dis ; 1863(1): 284-291, 2017 01.
Article em En | MEDLINE | ID: mdl-27815040

Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Síndrome MELAS / Complexo I de Transporte de Elétrons / Corpos Cetônicos / Mitocôndrias / Neurônios Limite: Humans Idioma: En Revista: Biochim Biophys Acta Mol Basis Dis Ano de publicação: 2017 Tipo de documento: Article País de afiliação: França

Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Síndrome MELAS / Complexo I de Transporte de Elétrons / Corpos Cetônicos / Mitocôndrias / Neurônios Limite: Humans Idioma: En Revista: Biochim Biophys Acta Mol Basis Dis Ano de publicação: 2017 Tipo de documento: Article País de afiliação: França