Toll-Like Receptor 2, Toll-Like Receptor 4, Myeloid Differentiation Response Gene 88, and Toll-IL-1 Receptor Domain-Containing Adaptor-Inducing Interferon-Î³ (TRIF) Selectively Regulate Susceptibility of P0<sub>106-125</sub>-Induced Murine Experimental Autoimmune Neuritis.

Brunn, Anna; Mihelcic, Mirna; Carstov, Mariana; Feind, Lisa; Wieser, Eva C; Schmidt, Julia; Utermöhlen, Olaf; Deckert, Martina

Toll-Like Receptor 2, Toll-Like Receptor 4, Myeloid Differentiation Response Gene 88, and Toll-IL-1 Receptor Domain-Containing Adaptor-Inducing Interferon-Î³ (TRIF) Selectively Regulate Susceptibility of P0_106-125-Induced Murine Experimental Autoimmune Neuritis.

Brunn, Anna; Mihelcic, Mirna; Carstov, Mariana; Feind, Lisa; Wieser, Eva C; Schmidt, Julia; Utermöhlen, Olaf; Deckert, Martina.

Afiliação

Brunn A; Department of Neuropathology, University Hospital of Cologne, Cologne, Germany. Electronic address: anna.brunn@uk-koeln.de.
Mihelcic M; Department of Neuropathology, University Hospital of Cologne, Cologne, Germany.
Carstov M; Department of Neuropathology, University Hospital of Cologne, Cologne, Germany.
Feind L; Department of Neuropathology, University Hospital of Cologne, Cologne, Germany.
Wieser EC; Department of Neuropathology, University Hospital of Cologne, Cologne, Germany.
Schmidt J; Department of Neuropathology, University Hospital of Cologne, Cologne, Germany.
Utermöhlen O; Institute for Medical Microbiology, Immunology, and Hygiene, Medical Center, University of Cologne, Cologne, Germany; Center for Molecular Medicine, Cologne, Germany.
Deckert M; Department of Neuropathology, University Hospital of Cologne, Cologne, Germany.

Am J Pathol ; 187(1): 42-54, 2017 Jan.

Article em En | MEDLINE | ID: mdl-27842213

Assuntos

Proteínas Adaptadoras de Transporte Vesicular/metabolismo; Fator 88 de Diferenciação Mieloide/metabolismo; Neurite Autoimune Experimental/metabolismo; Neurite Autoimune Experimental/patologia; Receptor 2 Toll-Like/metabolismo; Receptor 4 Toll-Like/metabolismo; Animais; Axônios/patologia; Linfócitos T CD4-Positivos/imunologia; Complemento C1q/imunologia; Progressão da Doença; Suscetibilidade a Doenças; Imunoglobulina G/sangue; Imunoglobulina M/sangue; Interferon gama/genética; Interferon gama/metabolismo; Contagem de Linfócitos; Ativação de Macrófagos; Metaloproteinase 2 da Matriz/metabolismo; Camundongos Endogâmicos C57BL; Músculo Esquelético/inervação; Músculo Esquelético/patologia; Proteína P0 da Mielina; NF-kappa B/metabolismo; Neurite Autoimune Experimental/sangue; Neurite Autoimune Experimental/imunologia; Ligante OX40/metabolismo; RNA Mensageiro/genética; RNA Mensageiro/metabolismo; Receptores OX40/metabolismo; Nervo Isquiático/metabolismo; Nervo Isquiático/patologia; Transdução de Sinais; Baço/metabolismo

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Proteínas Adaptadoras de Transporte Vesicular / Receptor 2 Toll-Like / Receptor 4 Toll-Like / Fator 88 de Diferenciação Mieloide / Neurite Autoimune Experimental Limite: Animals Idioma: En Revista: Am J Pathol Ano de publicação: 2017 Tipo de documento: Article

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