Clinical usefulness of narrow band imaging magnifying colonoscopy for assessing ulcerative colitis-associated cancer/dysplasia.
Endosc Int Open
; 4(11): E1183-E1187, 2016 Nov.
Article
em En
| MEDLINE
| ID: mdl-27853744
ABSTRACT
Background and study aims:
Colitis-associated cancer/dysplasia (CC/D) can affect the life expectancy of patients with ulcerative colitis (UC). Although the utility of magnifying chromocolonoscopy has been shown, the use of optical magnification with narrow band imaging (NBI) for distinguishing CC/D from non-neoplastic lesions in patients with UC has not been reported. We evaluated whether endoscopic findings are distinguishing and thus assessed the clinical usefulness of NBI magnification for differentiating UC-associated lesions. Patients andmethods:
The study involved 27 patients diagnosed and treated at Hiroshima University Hospital between September 2005 and March 2015 a neoplasia group (16 lesions) and a non-neoplasia group (17 lesions). The neoplasias comprised 9 dysplastic lesions, 5 intramucosal carcinomas, and 2 submucosal carcinomas, and 17 non-neoplastic lesions. Targeted biopsy samples of suspicious lesions detected by conventional colonoscopy were classified pathologically as neoplastic or non-neoplastic, and NBI magnifying colonoscopy findings (i.âe., the surface [unclear/regular/irregular/amorphous] and vascular [same as the background mucosa/regular/irregular/avascular] patterns) of the 2 lesion types were compared.Results:
Irregular/amorphous surface patterns were significantly more common in neoplastic lesions than in non-neoplastic lesions (81â% [13/16] vs. 18â% [3/17], respectively, Pâ<â0.001). Irregular/avascular vessel pattern tended to be more common in neoplastic lesions (75â% [12/16] vs. 41â% [7/17], respectively). The surface pattern correctly predicted 82â% of neoplastic lesions, and the vessel pattern correctly predicted 67â% of non-neoplastic lesions. The 2 endoscopic findings together correctly predicted 91â% of neoplastic lesions.Conclusion:
Surface pattern, determined by magnifying colonoscopy with NBI, is useful for differenting between UC-associated neoplastic and non-neoplastic lesions.
Texto completo:
1
Coleções:
01-internacional
Temas:
Geral
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Tipos_de_cancer
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Outros_tipos
Base de dados:
MEDLINE
Tipo de estudo:
Prognostic_studies
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Risk_factors_studies
Idioma:
En
Revista:
Endosc Int Open
Ano de publicação:
2016
Tipo de documento:
Article
País de afiliação:
Japão