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AIE fluorophore with enhanced cellular uptake for tracking esterase-activated release of taurine and ROS scavenging.
Wang, Jun; Wu, Yinglong; Zeng, Fang; Huang, Shuailing; Wu, Shuizhu.
Afiliação
  • Wang J; College of Materials Science and Engineering, State Key Laboratory of Luminescent Materials and Devices, South China University of Technology, Guangzhou 510640, P. R. China. mcfzeng@scut.edu.cn shzhwu@scut.edu.cn.
  • Wu Y; College of Materials Science and Engineering, State Key Laboratory of Luminescent Materials and Devices, South China University of Technology, Guangzhou 510640, P. R. China. mcfzeng@scut.edu.cn shzhwu@scut.edu.cn.
  • Zeng F; College of Materials Science and Engineering, State Key Laboratory of Luminescent Materials and Devices, South China University of Technology, Guangzhou 510640, P. R. China. mcfzeng@scut.edu.cn shzhwu@scut.edu.cn.
  • Huang S; College of Materials Science and Engineering, State Key Laboratory of Luminescent Materials and Devices, South China University of Technology, Guangzhou 510640, P. R. China. mcfzeng@scut.edu.cn shzhwu@scut.edu.cn.
  • Wu S; College of Materials Science and Engineering, State Key Laboratory of Luminescent Materials and Devices, South China University of Technology, Guangzhou 510640, P. R. China. mcfzeng@scut.edu.cn shzhwu@scut.edu.cn.
Faraday Discuss ; 196: 335-350, 2017 02 22.
Article em En | MEDLINE | ID: mdl-27892561
ABSTRACT
Fluorophores with aggregation-induced emission (AIE) characteristics are attractive and versatile tools for both chemical sensing and biological imaging. Herein, we designed and synthesized a fluorescent light-up system CTPE-Tau with enhanced cellular uptake ability. The system possesses several advantages, such as a large Stokes shift, low cytotoxicity, and good photostability. Also, it has been successfully utilized to track esterase-activated release of taurine and to scavenge intracellular ROS, and shows great potential for trackable visualized therapy.
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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Taurina / Espécies Reativas de Oxigênio / Esterases / Fluorescência / Corantes Fluorescentes Limite: Animals Idioma: En Revista: Faraday Discuss Assunto da revista: QUIMICA Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Taurina / Espécies Reativas de Oxigênio / Esterases / Fluorescência / Corantes Fluorescentes Limite: Animals Idioma: En Revista: Faraday Discuss Assunto da revista: QUIMICA Ano de publicação: 2017 Tipo de documento: Article