AIE fluorophore with enhanced cellular uptake for tracking esterase-activated release of taurine and ROS scavenging.
Faraday Discuss
; 196: 335-350, 2017 02 22.
Article
em En
| MEDLINE
| ID: mdl-27892561
ABSTRACT
Fluorophores with aggregation-induced emission (AIE) characteristics are attractive and versatile tools for both chemical sensing and biological imaging. Herein, we designed and synthesized a fluorescent light-up system CTPE-Tau with enhanced cellular uptake ability. The system possesses several advantages, such as a large Stokes shift, low cytotoxicity, and good photostability. Also, it has been successfully utilized to track esterase-activated release of taurine and to scavenge intracellular ROS, and shows great potential for trackable visualized therapy.
Texto completo:
1
Coleções:
01-internacional
Temas:
Geral
Base de dados:
MEDLINE
Assunto principal:
Taurina
/
Espécies Reativas de Oxigênio
/
Esterases
/
Fluorescência
/
Corantes Fluorescentes
Limite:
Animals
Idioma:
En
Revista:
Faraday Discuss
Assunto da revista:
QUIMICA
Ano de publicação:
2017
Tipo de documento:
Article