Tumor-Associated Lymphatic Vessels Upregulate PDL1 to Inhibit T-Cell Activation.

Dieterich, Lothar C; Ikenberg, Kristian; Cetintas, Timur; Kapaklikaya, Kübra; Hutmacher, Cornelia; Detmar, Michael

Dieterich, Lothar C; Ikenberg, Kristian; Cetintas, Timur; Kapaklikaya, Kübra; Hutmacher, Cornelia; Detmar, Michael.

Afiliação

Dieterich LC; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology (ETH) Zurich , Zurich , Switzerland.
Ikenberg K; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology (ETH) Zurich, Zurich, Switzerland; Department of Pathology and Molecular Pathology, University Hospital Zurich, Zurich, Switzerland.
Cetintas T; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology (ETH) Zurich , Zurich , Switzerland.
Kapaklikaya K; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology (ETH) Zurich , Zurich , Switzerland.
Hutmacher C; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology (ETH) Zurich , Zurich , Switzerland.
Detmar M; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology (ETH) Zurich , Zurich , Switzerland.

Front Immunol ; 8: 66, 2017.

Article em En | MEDLINE | ID: mdl-28217128

Palavras-chave

PD1; T-cell exhaustion; abortive proliferation; immune checkpoint; lymph node; peripheral tolerance; tumor vasculature; tumor-induced immunosuppression

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Front Immunol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Suíça

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