Recent developments in radiotherapy for small-cell lung cancer: a review by the Oncologic Group for the Study of Lung Cancer (Spanish Radiation Oncology Society).
Clin Transl Oncol
; 19(10): 1183-1192, 2017 Oct.
Article
em En
| MEDLINE
| ID: mdl-28447257
ABSTRACT
Small-cell lung cancer (SCLC) accounts for 13% of all lung tumours. The standard treatment in patients with limited-stage disease is radiotherapy combined with chemotherapy. In extensive SCLC, the importance of consolidation thoracic radiotherapy in patients with a good treatment response has become increasingly recognized. In both limited and extensive disease, prophylactic cranial irradiation is recommended in patients who respond to treatment. New therapeutic approaches such as immunotherapy are being increasingly incorporated into the treatment of SCLC, although more slowly than in non-small cell lung cancer (NSCLC). Diverse radiation dose and fractionation schemes, administered in varying combinations with these new drugs, are being investigated. In the present study we review and update the role of radiotherapy in the treatment of SCLC. We also discuss the main clinical trials currently underway in order to identify future trends.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Temas:
Geral
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Prevencao_e_fatores_de_risco
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Agentes_cancerigenos
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Tipos_de_cancer
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Pulmao
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Tratamento
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Radioterapia
Base de dados:
MEDLINE
Assunto principal:
Radioterapia (Especialidade)
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Fracionamento da Dose de Radiação
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Carcinoma de Pequenas Células do Pulmão
Limite:
Humans
Idioma:
En
Revista:
Clin Transl Oncol
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Espanha