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Tmbim1 is a multivesicular body regulator that protects against non-alcoholic fatty liver disease in mice and monkeys by targeting the lysosomal degradation of Tlr4.
Zhao, Guang-Nian; Zhang, Peng; Gong, Jun; Zhang, Xiao-Jing; Wang, Pi-Xiao; Yin, Miao; Jiang, Zhou; Shen, Li-Jun; Ji, Yan-Xiao; Tong, Jingjing; Wang, Yutao; Wei, Qiao-Fang; Wang, Yong; Zhu, Xue-Yong; Zhang, Xin; Fang, Jing; Xie, Qingguo; She, Zhi-Gang; Wang, Zhihua; Huang, Zan; Li, Hongliang.
Afiliação
  • Zhao GN; Medical Science Research Center, Zhongnan Hospital of Wuhan University, Wuhan, China.
  • Zhang P; Basic Medical School, Wuhan University, Wuhan, China.
  • Gong J; Institute of Model Animal of Wuhan University, Wuhan, China.
  • Zhang XJ; Medical Research Institute, School of Medicine, Wuhan University, Wuhan, China.
  • Wang PX; College of Life Sciences, Wuhan University, Wuhan, China.
  • Yin M; Medical Science Research Center, Zhongnan Hospital of Wuhan University, Wuhan, China.
  • Jiang Z; Basic Medical School, Wuhan University, Wuhan, China.
  • Shen LJ; Institute of Model Animal of Wuhan University, Wuhan, China.
  • Ji YX; Medical Research Institute, School of Medicine, Wuhan University, Wuhan, China.
  • Tong J; Basic Medical School, Wuhan University, Wuhan, China.
  • Wang Y; Institute of Model Animal of Wuhan University, Wuhan, China.
  • Wei QF; Medical Research Institute, School of Medicine, Wuhan University, Wuhan, China.
  • Wang Y; College of Life Sciences, Wuhan University, Wuhan, China.
  • Zhu XY; Basic Medical School, Wuhan University, Wuhan, China.
  • Zhang X; Institute of Model Animal of Wuhan University, Wuhan, China.
  • Fang J; Medical Research Institute, School of Medicine, Wuhan University, Wuhan, China.
  • Xie Q; Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
  • She ZG; Basic Medical School, Wuhan University, Wuhan, China.
  • Wang Z; Institute of Model Animal of Wuhan University, Wuhan, China.
  • Huang Z; Medical Research Institute, School of Medicine, Wuhan University, Wuhan, China.
  • Li H; Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Nat Med ; 23(6): 742-752, 2017 Jun.
Article em En | MEDLINE | ID: mdl-28481357
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Prevencao_e_fatores_de_risco / Alcoolismo Base de dados: MEDLINE Assunto principal: Proteínas Reguladoras de Apoptose / Receptor 4 Toll-Like / Corpos Multivesiculares / Hepatopatia Gordurosa não Alcoólica / Proteínas de Membrana Limite: Adolescent / Adult / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Med Assunto da revista: BIOLOGIA MOLECULAR / MEDICINA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: China
Texto completo
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Prevencao_e_fatores_de_risco / Alcoolismo Base de dados: MEDLINE Assunto principal: Proteínas Reguladoras de Apoptose / Receptor 4 Toll-Like / Corpos Multivesiculares / Hepatopatia Gordurosa não Alcoólica / Proteínas de Membrana Limite: Adolescent / Adult / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Med Assunto da revista: BIOLOGIA MOLECULAR / MEDICINA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: China