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CDK4 phosphorylation status and a linked gene expression profile predict sensitivity to palbociclib.
Raspé, Eric; Coulonval, Katia; Pita, Jaime M; Paternot, Sabine; Rothé, Françoise; Twyffels, Laure; Brohée, Sylvain; Craciun, Ligia; Larsimont, Denis; Kruys, Véronique; Sandras, Flavienne; Salmon, Isabelle; Van Laere, Steven; Piccart, Martine; Ignatiadis, Michail; Sotiriou, Christos; Roger, Pierre P.
Afiliação
  • Raspé E; WELBIO and Institute of Interdisciplinary Research (IRIBHM), Campus Erasme, Université Libre de Bruxelles (ULB), Brussels, Belgium eraspe@ulb.ac.be christos.sotiriou@bordet.be proger@ulb.ac.be.
  • Coulonval K; ULB-Cancer Research Center (U-CRC) Université Libre de Bruxelles, Brussels, Belgium.
  • Pita JM; WELBIO and Institute of Interdisciplinary Research (IRIBHM), Campus Erasme, Université Libre de Bruxelles (ULB), Brussels, Belgium.
  • Paternot S; ULB-Cancer Research Center (U-CRC) Université Libre de Bruxelles, Brussels, Belgium.
  • Rothé F; WELBIO and Institute of Interdisciplinary Research (IRIBHM), Campus Erasme, Université Libre de Bruxelles (ULB), Brussels, Belgium.
  • Twyffels L; ULB-Cancer Research Center (U-CRC) Université Libre de Bruxelles, Brussels, Belgium.
  • Brohée S; WELBIO and Institute of Interdisciplinary Research (IRIBHM), Campus Erasme, Université Libre de Bruxelles (ULB), Brussels, Belgium.
  • Craciun L; ULB-Cancer Research Center (U-CRC) Université Libre de Bruxelles, Brussels, Belgium.
  • Larsimont D; ULB-Cancer Research Center (U-CRC) Université Libre de Bruxelles, Brussels, Belgium.
  • Kruys V; Breast Cancer Translational Research Laboratory, Institut Jules Bordet, Université Libre de Bruxelles (ULB), Brussels, Belgium.
  • Sandras F; Laboratoire de Biologie Moléculaire du Gène, Faculté des Sciences, Université libre de Bruxelles (ULB), Brussels, Belgium.
  • Salmon I; Center for Microscopy and Molecular Imaging, Université Libre de Bruxelles (ULB), Brussels, Belgium.
  • Van Laere S; ULB-Cancer Research Center (U-CRC) Université Libre de Bruxelles, Brussels, Belgium.
  • Piccart M; Breast Cancer Translational Research Laboratory, Institut Jules Bordet, Université Libre de Bruxelles (ULB), Brussels, Belgium.
  • Ignatiadis M; Tumor Bank of the Jules Bordet Institute, Université Libre de Bruxelles (ULB), Brussels, Belgium.
  • Sotiriou C; Department of Pathology, Institut Jules Bordet, Université Libre de Bruxelles (ULB), Brussels, Belgium.
  • Roger PP; Laboratoire de Biologie Moléculaire du Gène, Faculté des Sciences, Université libre de Bruxelles (ULB), Brussels, Belgium.
EMBO Mol Med ; 9(8): 1052-1066, 2017 08.
Article em En | MEDLINE | ID: mdl-28566333
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Prevencao_e_fatores_de_risco / Agentes_cancerigenos / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Piperazinas / Piridinas / Neoplasias da Mama / Processamento de Proteína Pós-Traducional / Quinase 4 Dependente de Ciclina / Transcriptoma / Antineoplásicos Tipo de estudo: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans Idioma: En Revista: EMBO Mol Med Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Prevencao_e_fatores_de_risco / Agentes_cancerigenos / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Piperazinas / Piridinas / Neoplasias da Mama / Processamento de Proteína Pós-Traducional / Quinase 4 Dependente de Ciclina / Transcriptoma / Antineoplásicos Tipo de estudo: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans Idioma: En Revista: EMBO Mol Med Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2017 Tipo de documento: Article