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Selinexor-induced thrombocytopenia results from inhibition of thrombopoietin signaling in early megakaryopoiesis.
Machlus, Kellie R; Wu, Stephen K; Vijey, Prakrith; Soussou, Thomas S; Liu, Zhi-Jian; Shacham, Eran; Unger, T J; Kashyap, Trinayan; Klebanov, Boris; Sola-Visner, Martha; Crochiere, Marsha; Italiano, Joseph E; Landesman, Yosef.
Afiliação
  • Machlus KR; Division of Hematology, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.
  • Wu SK; Division of Hematology, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.
  • Vijey P; Division of Hematology, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.
  • Soussou TS; Division of Hematology, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.
  • Liu ZJ; Department of Pediatrics, Harvard Medical School, Boston, MA.
  • Shacham E; Division of New Born Medicine, Boston Children's Hospital, Boston, MA.
  • Unger TJ; Karyopharm Therapeutics, Newton, MA; and.
  • Kashyap T; Karyopharm Therapeutics, Newton, MA; and.
  • Klebanov B; Karyopharm Therapeutics, Newton, MA; and.
  • Sola-Visner M; Karyopharm Therapeutics, Newton, MA; and.
  • Crochiere M; Department of Pediatrics, Harvard Medical School, Boston, MA.
  • Italiano JE; Division of New Born Medicine, Boston Children's Hospital, Boston, MA.
  • Landesman Y; Karyopharm Therapeutics, Newton, MA; and.
Blood ; 130(9): 1132-1143, 2017 08 31.
Article em En | MEDLINE | ID: mdl-28630120
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tratamento / Transplante_de_medula_ossea Base de dados: MEDLINE Assunto principal: Trombocitopenia / Trombopoetina / Triazóis / Megacariócitos / Transdução de Sinais / Trombopoese / Hidrazinas Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Blood Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Marrocos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tratamento / Transplante_de_medula_ossea Base de dados: MEDLINE Assunto principal: Trombocitopenia / Trombopoetina / Triazóis / Megacariócitos / Transdução de Sinais / Trombopoese / Hidrazinas Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Blood Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Marrocos